Nielsen J, Damkier P, Lublin H, Taylor D. Optimizing clozapine treatment. Objective:
Clozapine treatment remains the gold standard for treatment‐resistant schizophrenia, but …

Generic medications do not undergo the rigorous approval process required of original
medications. Their effectiveness and safety is expected to be equal to that of their more …

Pharmaceutical expenditures in ambulatory care rose rapidly in Europe in the 1990s and
early 2000s. This was typically faster than other components of healthcare spending …

Drugs in the bisphosphonate class are the most commonly prescribed therapeutic agents for
the treatment of osteoporosis. Prospective, randomized, placebo-controlled clinical trials …

Pressures to contain pharmaceutical expenditure have led to increased prescribing and
dispensing of generic drugs in addition to low prices for generics. Atypical antipsychotics are …

The number of newly approved generic psychotropic drugs increases every year and, in
many countries, their sales exceed the sales of brand-name counterparts. In order for any …

Objective Clozapine is considered the most reliable drug for treatment-resistant
schizophrenia. In 2014, a generic formulation of clozapine (Clzapine) was introduced in …

Purpose. The effectiveness and tolerability of switching patients' therapy from brand-name to
generic clozapine are reviewed. Summary. Clozapine is the most effective treatment for …

Background: Several reports of loss of efficacy or adverse effects have been described after
generic substitution of antipsychotics. To date, studies comparing serum drug levels in …

Abstract Background Original sevoflurane (Sevofrane) contains a small amount of water,
which can inhibit the production of hydrofluoric acid. Hydrofluoric acid is highly pungent, and …