Microfluidic cell sorting: a review of the advances in the separation of cells from debulking to rare cell isolation

CW Shields Iv, CD Reyes, GP López - Lab on a Chip, 2015 - pubs.rsc.org
Accurate and high throughput cell sorting is a critical enabling technology in molecular and
cellular biology, biotechnology, and medicine. While conventional methods can provide high …

Acoustic tweezers

L Meng, F Cai, F Li, W Zhou, L Niu… - Journal of Physics D …, 2019 - iopscience.iop.org
Acoustic tweezers are gaining increasing attention as a noncontact method that is capable
of handling microparticles and nanoparticles in a controllable manner. By designing the …

Biomolecular actuators for genetically selective acoustic manipulation of cells

D Wu, D Baresch, C Cook, Z Ma, M Duan… - Science …, 2023 - science.org
The ability to physically manipulate specific cells is critical for the fields of biomedicine,
synthetic biology, and living materials. Ultrasound has the ability to manipulate cells with …

Iso-acoustic focusing of cells for size-insensitive acousto-mechanical phenotyping

P Augustsson, JT Karlsen, HW Su, H Bruus… - Nature …, 2016 - nature.com
Mechanical phenotyping of single cells is an emerging tool for cell classification, enabling
assessment of effective parameters relating to cells' interior molecular content and structure …

Forces acting on a small particle in an acoustical field in a thermoviscous fluid

JT Karlsen, H Bruus - Physical Review E, 2015 - APS
We present a theoretical analysis of the acoustic radiation force on a single small spherical
particle, either a thermoviscous fluid droplet or a thermoelastic solid particle, suspended in a …

Microfluidic sample preparation for single cell analysis

S Hosic, SK Murthy, AN Koppes - Analytical chemistry, 2016 - ACS Publications
Single cell analysis is the measurement of transcription, translation, regulatory, and
signaling events within individual cells at the molecular level. The goal is to analyze and …

Two-step acoustophoresis separation of live tumor cells from whole blood

E Undvall Anand, C Magnusson, A Lenshof… - Analytical …, 2021 - ACS Publications
There is an unmet clinical need to extract living circulating tumor cells (CTCs) for functional
studies and in vitro expansion to enable drug testing and predict responses to therapy in …

Acoustofluidic synthesis of particulate nanomaterials

PH Huang, S Zhao, H Bachman, N Nama… - Advanced …, 2019 - Wiley Online Library
Synthesis of nanoparticles and particulate nanomaterials with tailored properties is a central
step toward many applications ranging from energy conversion and imaging/display to …

Organs-on-chip monitoring: sensors and other strategies

T Kilic, F Navaee, F Stradolini… - Microphysiological …, 2018 - infoscience.epfl.ch
As a paradigm shifting player of tissue engineering, organs-on-chips (OOCs) are considered
to hold great potential for future “clinical trials on chip” as well as a step forward to design …

Recent advances in microfluidic technology for manipulation and analysis of biological cells (2007–2017)

MK Alam, E Koomson, H Zou, C Yi, CW Li, T Xu… - Analytica chimica …, 2018 - Elsevier
The pivotal role of microfluidic technology in life science and biomedical research is now
widely recognized. Indeed, microfluidics as a research tool is unparalleled in terms of its …