An update on immunopathogenesis, diagnosis, and treatment of multiple sclerosis

N Garg, TW Smith - Brain and behavior, 2015 - Wiley Online Library
Background Multiple sclerosis is an acquired demyelinating disease of the central nervous
system. It is the second most common cause of disability in adults in United States after head …

Physical activity and autoimmune diseases: Get moving and manage the disease

K Sharif, A Watad, NL Bragazzi, M Lichtbroun… - Autoimmunity …, 2018 - Elsevier
Physical activity, by definition, is any skeletal muscle body movement that results in energy
expenditure. In the last few decades, a plethora of scientific evidences have accumulated …

Evaluation of no evidence of disease activity in a 7-year longitudinal multiple sclerosis cohort

DL Rotstein, BC Healy, MT Malik, T Chitnis… - JAMA …, 2015 - jamanetwork.com
Importance With multiple and increasingly effective therapies for relapsing forms of multiple
sclerosis (MS), disease-free status or no evidence of disease activity (NEDA) has become a …

Natural history of multiple sclerosis symptoms

I Kister, TE Bacon, E Chamot… - … journal of MS care, 2013 - meridian.allenpress.com
The North American Research Committee on Multiple Sclerosis (NARCOMS) Registry is a
database that contains information from over 35,000 patient volunteers on symptom severity …

Profiling walking dysfunction in multiple sclerosis: characterisation, classification and progression over time

L Filli, T Sutter, CS Easthope, T Killeen, C Meyer… - Scientific reports, 2018 - nature.com
Gait dysfunction is a common and relevant symptom in multiple sclerosis (MS). This study
aimed to profile gait pathology in gait-impaired patients with MS using comprehensive 3D …

An argument for broad use of high efficacy treatments in early multiple sclerosis

JM Stankiewicz, HL Weiner - Neurology: Neuroimmunology & …, 2019 - AAN Enterprises
Two different treatment paradigms are most often used in multiple sclerosis (MS). An
escalation or induction approach is considered when treating a patient early in the disease …

Harnessing real-world data to inform decision-making: Multiple Sclerosis Partners Advancing Technology and Health Solutions (MS PATHS)

EM Mowry, RA Bermel, JR Williams… - Frontiers in …, 2020 - frontiersin.org
Background: Multiple Sclerosis Partners Advancing Technology and Health Solutions (MS
PATHS) is the first example of a learning health system in multiple sclerosis (MS). This paper …

Hispanic Americans and African Americans with multiple sclerosis have more severe disease course than Caucasian Americans

RE Ventura, AO Antezana, T Bacon… - Multiple Sclerosis …, 2017 - journals.sagepub.com
Whether disease course in Hispanic Americans (HA) with multiple sclerosis (MS) is different
from Caucasian Americans (CA) or African Americans (AA) is unknown. We compared MS …

Association of disease severity and socioeconomic status in Black and White Americans with multiple sclerosis

K Gray-Roncal, KC Fitzgerald, LZ Ryerson, L Charvet… - Neurology, 2021 - AAN Enterprises
Objective To compare clinical and imaging features of multiple sclerosis (MS) severity
between Black Americans (BAs) and White Americans (WAs) and to evaluate the role of …

Fall risk prediction in multiple sclerosis using postural sway measures: a machine learning approach

R Sun, KL Hsieh, JJ Sosnoff - Scientific reports, 2019 - nature.com
Numerous postural sway metrics have been shown to be sensitive to balance impairment
and fall risk in individuals with MS. Yet, there are no guidelines concerning the most …