Photodynamic and photothermal therapies: synergy opportunities for nanomedicine
Tumoricidal photodynamic (PDT) and photothermal (PTT) therapies harness light to
eliminate cancer cells with spatiotemporal precision by either generating reactive oxygen …
eliminate cancer cells with spatiotemporal precision by either generating reactive oxygen …
Photodynamic and antibiotic therapy in combination against bacterial infections: efficacy, determinants, mechanisms, and future perspectives
Antibiotic treatment, the mainstay for the control of bacterial infections, is greatly hampered
by the global prevalence of multidrug-resistant (MDR) bacteria. Photodynamic therapy (PDT) …
by the global prevalence of multidrug-resistant (MDR) bacteria. Photodynamic therapy (PDT) …
Malignant ascites in ovarian cancer: cellular, acellular, and biophysical determinants of molecular characteristics and therapy response
Simple Summary Accumulation of excess fluid in the abdomen typically indicates abnormal
function or disease, such as cancer, in the underlying tissues. This accumulation of fluid, or …
function or disease, such as cancer, in the underlying tissues. This accumulation of fluid, or …
Fluorescence-guided photoimmunotherapy using targeted nanotechnology and ML7710 to manage peritoneal carcinomatosis
Fluorescence-guided intervention can bolster standard therapies by detecting and treating
microscopic tumors before lethal recurrence. Tremendous progress in photoimmunotherapy …
microscopic tumors before lethal recurrence. Tremendous progress in photoimmunotherapy …
[HTML][HTML] Neutrophil-mimicking therapeutic nanoparticles for targeted chemotherapy of pancreatic carcinoma
X Cao, Y Hu, S Luo, Y Wang, T Gong, X Sun… - … Pharmaceutica Sinica B, 2019 - Elsevier
Due to the critical correlation between inflammation and carcinogenesis, a therapeutic
candidate with anti-inflammatory activity may find application in cancer therapy. Here, we …
candidate with anti-inflammatory activity may find application in cancer therapy. Here, we …
Impacting Pancreatic Cancer Therapy in Heterotypic in Vitro Organoids and in Vivo Tumors with Specificity-Tuned, NIR-Activable Photoimmunonanoconjugates …
Despite untiring efforts to develop therapies for pancreatic ductal adenocarcinoma (PDAC),
survival statistics remain dismal, necessitating distinct approaches. Photodynamic priming …
survival statistics remain dismal, necessitating distinct approaches. Photodynamic priming …
Photodynamic therapy and the biophysics of the tumor microenvironment
Targeting the tumor microenvironment (TME) provides opportunities to modulate tumor
physiology, enhance the delivery of therapeutic agents, impact immune response and …
physiology, enhance the delivery of therapeutic agents, impact immune response and …
Photodynamic therapy, priming and optical imaging: Potential co-conspirators in treatment design and optimization—a Thomas Dougherty Award for Excellence in …
Photodynamic therapy is a photochemistry-based approach, approved for the treatment of
several malignant and non-malignant pathologies. It relies on the use of a non-toxic, light …
several malignant and non-malignant pathologies. It relies on the use of a non-toxic, light …
Porphyrin-lipid stabilized paclitaxel nanoemulsion for combined photodynamic therapy and chemotherapy
Background Porphyrin-lipids are versatile building blocks that enable cancer theranostics
and have been applied to create several multimodal nanoparticle platforms, including …
and have been applied to create several multimodal nanoparticle platforms, including …
Remediating desmoplasia with EGFR‐targeted photoactivable multi‐inhibitor liposomes doubles overall survival in pancreatic cancer
Desmoplasia is characteristic of pancreatic ductal adenocarcinoma (PDAC), which exhibits
5‐year survival rates of 3%. Desmoplasia presents physical and biochemical barriers that …
5‐year survival rates of 3%. Desmoplasia presents physical and biochemical barriers that …