Flipside of the coin: iron deficiency and colorectal cancer

A Aksan, K Farrag, S Aksan, O Schroeder… - Frontiers in …, 2021 - frontiersin.org
Iron deficiency, with or without anemia, is the most frequent hematological manifestation in
individuals with cancer, and is especially common in patients with colorectal cancer. Iron is a …

Iron deficiency screening is a key issue in chronic inflammatory diseases: A call to action

P Cacoub, G Choukroun, A Cohen‐Solal… - Journal of Internal …, 2022 - Wiley Online Library
Iron deficiency is frequent in patients with chronic inflammatory conditions (eg, chronic heart
failure, chronic kidney disease, cancers, and bowel inflammatory diseases). Indeed, high …

Ferric carboxymaltose infusion versus oral iron supplementation for preoperative iron deficiency anaemia in patients with colorectal cancer (FIT): a multicentre, open …

K Talboom, WAA Borstlap, SX Roodbeen… - The Lancet …, 2023 - thelancet.com
Background A third of patients with colorectal cancer who are eligible for surgery in high-
income countries have concomitant anaemia associated with adverse outcomes. We aimed …

PPy@Fe3O4 nanoparticles inhibit the proliferation and metastasis of CRC via suppressing the NF-κB signaling pathway and promoting ferroptosis

Z Yu, S Tong, C Wang, Z Wu, Y Ye, S Wang… - … in Bioengineering and …, 2022 - frontiersin.org
Colorectal cancer (CRC) is one of the most common cancers of the digestive tract, and
patients with advanced-stage cancer have poor survival despite the use of multidrug …

[HTML][HTML] Preoperative intravenous iron treatment in colorectal cancer: experience from clinical practice

M Ploug, R Kroijer, N Qvist, T Knudsen - journal of surgical research, 2022 - Elsevier
Introduction Anemia is associated with increased postoperative morbidity and mortality in
abdominal surgery. In clinical trials, preoperative iv iron treatment increases the …

[HTML][HTML] Oxidative imbalance increases the risk for colonic polyp and colorectal cancer development

D Tsounis, V Villiotou, A Melpidou… - World Journal of …, 2022 - ncbi.nlm.nih.gov
BACKGROUND The role of oxidative stress in the pathogenesis of colorectal carcinoma
(CRC) has garnered considerable interest recently. Specific oxidative factors have been …

Assessment of the Impact of Trace Essential Metals on Cancer Development

A Górska, A Markiewicz-Gospodarek… - International Journal of …, 2024 - mdpi.com
This study examines the impact of zinc, copper, cobalt, iron, and manganese on cancer
development, considering their dual roles as potential promoters or inhibitors within …

Preoperative intravenous iron and the risk of blood transfusion in colorectal cancer surgery: meta-analysis of randomized clinical trials

H Lederhuber, LH Massey, S Abeysiri… - British Journal of …, 2024 - academic.oup.com
Preoperative anaemia commonly affects 30–60 per cent of the general surgical population,
and is associated with an increased risk of postoperative morbidity, prolonged hospital stay …

[HTML][HTML] Faecal immunochemical tests can improve colonoscopy triage in patients with iron deficiency: a systematic review and meta-analysis

J Pham, G Laven-Law, EL Symonds, MM Wassie… - Critical Reviews in …, 2024 - Elsevier
Background Use of the faecal immunochemical test (FIT) to triage patients with iron
deficiency (ID) for colonoscopy due to suspected colorectal cancer (CRC) may improve …

Absolute and Functional Iron Deficiency in Colon Cancer: A Cohort Study

V Făgărășan, D Andraș, G Amarinei, RI Seicean… - Medicina, 2022 - mdpi.com
Background and Objectives: Iron is an essential micronutrient for many biological functions
and has been found to be intimately linked to cancer biology. Although the effects of …