Effective delivery of therapeutic and diagnostic nanoparticles is dependent on their ability to
accumulate in diseased tissues. However, most nanoparticles end up in liver macrophages …

Despite the overwhelming success of vaccines in preventing infectious diseases, there
remain numerous globally devastating diseases without fully protective vaccines, particularly …

Nanoparticle-based technologies offer exciting new approaches to disease diagnostics and
therapeutics. To take advantage of unique properties of nanoscale materials and structures …

As an essential innate immune population for maintaining body homeostasis and warding
off foreign pathogens, macrophages display high plasticity and perform diverse supportive …

Surfactants, whose existence has been recognized as early as 2800 BC, have had a long
history with the development of human civilization. With the rapid development of …

Biotherapy has recently become a hotspot research topic with encouraging prospects in
various fields due to a wide range of treatments applications, as demonstrated in preclinical …

The immune system plays a critical role in our health. No other component of human
physiology plays a decisive role in as diverse an array of maladies, from deadly diseases …

Infectious diseases are the leading cause of mortality worldwide, with viruses in particular
making global impact on healthcare and socioeconomic development. In addition, the rapid …

Many types of nanoparticles (NPs) are tested for use in medical products, particularly in
imaging and gene and drug delivery. For these applications, cellular uptake is usually a …

When nanoparticles (NPs) enter a physiological environment, medium components compete
for binding to the NP surface leading to formation of a rich protein shell known as the …