Why nanoparticles prefer liver macrophage cell uptake in vivo
Effective delivery of therapeutic and diagnostic nanoparticles is dependent on their ability to
accumulate in diseased tissues. However, most nanoparticles end up in liver macrophages …
accumulate in diseased tissues. However, most nanoparticles end up in liver macrophages …
Advances in nanomaterial vaccine strategies to address infectious diseases impacting global health
Despite the overwhelming success of vaccines in preventing infectious diseases, there
remain numerous globally devastating diseases without fully protective vaccines, particularly …
remain numerous globally devastating diseases without fully protective vaccines, particularly …
The Effect of Nanoparticle Size on In Vivo Pharmacokinetics and Cellular Interaction
N Hoshyar, S Gray, H Han, G Bao - Nanomedicine, 2016 - Taylor & Francis
Nanoparticle-based technologies offer exciting new approaches to disease diagnostics and
therapeutics. To take advantage of unique properties of nanoscale materials and structures …
therapeutics. To take advantage of unique properties of nanoscale materials and structures …
Progress in tumor-associated macrophage (TAM)-targeted therapeutics
C Ngambenjawong, HH Gustafson, SH Pun - Advanced drug delivery …, 2017 - Elsevier
As an essential innate immune population for maintaining body homeostasis and warding
off foreign pathogens, macrophages display high plasticity and perform diverse supportive …
off foreign pathogens, macrophages display high plasticity and perform diverse supportive …
A critical review of the use of surfactant-coated nanoparticles in nanomedicine and food nanotechnology
T Miyazawa, M Itaya, GC Burdeos… - International journal …, 2021 - Taylor & Francis
Surfactants, whose existence has been recognized as early as 2800 BC, have had a long
history with the development of human civilization. With the rapid development of …
history with the development of human civilization. With the rapid development of …
Biomaterial-assisted biotherapy: A brief review of biomaterials used in drug delivery, vaccine development, gene therapy, and stem cell therapy
Biotherapy has recently become a hotspot research topic with encouraging prospects in
various fields due to a wide range of treatments applications, as demonstrated in preclinical …
various fields due to a wide range of treatments applications, as demonstrated in preclinical …
Synthetic nanoparticles for vaccines and immunotherapy
The immune system plays a critical role in our health. No other component of human
physiology plays a decisive role in as diverse an array of maladies, from deadly diseases …
physiology plays a decisive role in as diverse an array of maladies, from deadly diseases …
The role of nanotechnology in the treatment of viral infections
L Singh, HG Kruger, GEM Maguire… - Therapeutic …, 2017 - journals.sagepub.com
Infectious diseases are the leading cause of mortality worldwide, with viruses in particular
making global impact on healthcare and socioeconomic development. In addition, the rapid …
making global impact on healthcare and socioeconomic development. In addition, the rapid …
The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles
E Fröhlich - International journal of nanomedicine, 2012 - Taylor & Francis
Many types of nanoparticles (NPs) are tested for use in medical products, particularly in
imaging and gene and drug delivery. For these applications, cellular uptake is usually a …
imaging and gene and drug delivery. For these applications, cellular uptake is usually a …
Effect of polyethyleneglycol (PEG) chain length on the bio–nano-interactions between PEGylated lipid nanoparticles and biological fluids: from nanostructure to uptake …
D Pozzi, V Colapicchioni, G Caracciolo, S Piovesana… - Nanoscale, 2014 - pubs.rsc.org
When nanoparticles (NPs) enter a physiological environment, medium components compete
for binding to the NP surface leading to formation of a rich protein shell known as the …
for binding to the NP surface leading to formation of a rich protein shell known as the …