Small angle X-ray fiber diffraction is the method of choice for obtaining molecular level
structural information from striated muscle fibers under hydrated physiological conditions …

Skeletal muscle, a highly complex muscle type in the eukaryotic system, is characterized by
different muscle subtypes and functions associated with specific myosin isoforms. As a …

Muscle contraction is produced via the interaction of myofilaments and is regulated so that
muscle performance matches demand. Myosin-binding protein C (MyBP-C) is a long and …

Aging slowly erodes skeletal muscle strength and mass, eventually leading to profound
functional deficits and muscle atrophy. The molecular mechanisms of skeletal muscle aging …

Sustained muscle contraction occurs through interactions between actin and myosin
filaments within sarcomeres and requires a constant supply of adenosine triphosphate (ATP) …

Hibernation is a period of metabolic suppression utilized by many small and large mammal
species to survive during winter periods. As the underlying cellular and molecular …

The coverage of the protein database directly determines the results of shotgun proteomics.
In this study, PacBio single-molecule real-time sequencing technology was performed on …

Myosin-binding protein H (MyBP-H) is a component of the vertebrate skeletal muscle
sarcomere with sequence and domain homology to myosin-binding protein C (MyBP-C) …

The ACTN2 gene encodes α-actinin 2, located in the Z-disc of the sarcomeres in striated
muscle. In this study, we sought to investigate the effects of an ACTN2 missense variant of …

Skeletal muscles produce forces relatively slowly compared with the action potentials that
excite them. The dynamics of force production are governed by multiple processes, such as …