The neural mechanisms of manual dexterity

AR Sobinov, SJ Bensmaia - Nature Reviews Neuroscience, 2021 - nature.com
The hand endows us with unparalleled precision and versatility in our interactions with
objects, from mundane activities such as grasping to extraordinary ones such as virtuoso …

[HTML][HTML] Diabetes mellitus-related dysfunction of the motor system

K Muramatsu - International journal of molecular sciences, 2020 - mdpi.com
Although motor deficits in humans with diabetic neuropathy have been extensively
researched, its effect on the motor system is thought to be lesser than that on the sensory …

Rapid and bihemispheric reorganization of neuronal activity in premotor cortex after brain injury

I Moreau-Debord, É Serrano, S Quessy… - Journal of …, 2021 - Soc Neuroscience
Brain injuries cause hemodynamic changes in several distant, spared areas from the lesion.
Our objective was to better understand the neuronal correlates of this reorganization in …

[HTML][HTML] Mesenchymal-derived extracellular vesicles enhance microglia-mediated synapse remodeling after cortical injury in aging Rhesus monkeys

Y Zhou, H Bhatt, CA Mojica, H Xin, MA Pessina… - Journal of …, 2023 - Springer
Understanding the microglial neuro-immune interactions in the primate brain is vital to
developing therapeutics for cortical injury, such as stroke or traumatic brain injury. Our …

Non-human primate models of focal cortical ischemia for neuronal replacement therapy

J Mu, P Hao, H Duan, W Zhao… - Journal of Cerebral …, 2023 - journals.sagepub.com
Despite the high prevalence, stroke remains incurable due to the limited regeneration
capacity in the central nervous system. Neuronal replacement strategies are highly diverse …

Extremely preterm infants with a near-total absence of cerebellum: usefulness of quantitative magnetic resonance in predicting the motor outcome

R Calandrelli, L Tuzza, DM Romeo, C Arpaia… - The Cerebellum, 2024 - Springer
This study aims to evaluate in extremely premature infants the severity of brain structural
injury causing total absence or near-total absence of cerebellar hemispheres by using MRI …

[HTML][HTML] Non-human primate models to explore the adaptive mechanisms after stroke

N Higo - Frontiers in Systems Neuroscience, 2021 - frontiersin.org
The brain has the ability to reconstruct neural structures and functions to compensate for the
brain lesions caused by stroke, although it is highly limited in primates including humans …

Pharmacological inactivation of the primate posterior insular/secondary somatosensory cortices attenuates thermal hyperalgesia

K Nagasaka, I Takashima, K Matsuda… - European Journal of …, 2022 - Wiley Online Library
Background We previously established a macaque model of central post‐stroke pain
(CPSP) and confirmed the involvement of increased activity of the posterior insular cortex …

Structural plastic changes of cortical gray matter revealed by voxel-based morphometry and histological analyses in a monkey model of central post-stroke pain

K Nagasaka, K Nemoto, I Takashima, D Bando… - Cerebral …, 2021 - academic.oup.com
Central post-stroke pain (CPSP) is a chronic pain caused by stroke lesions of
somatosensory pathways. Several brain imaging studies among patients with CPSP …

[HTML][HTML] Functional near-infrared-spectroscopy-based measurement of changes in cortical activity in macaques during post-infarct recovery of manual dexterity

J Kato, T Yamada, H Kawaguchi, K Matsuda… - Scientific Reports, 2020 - nature.com
Because compensatory changes in brain activity underlie functional recovery after brain
damage, monitoring of these changes will help to improve rehabilitation effectiveness …