Objective Central sensitization (CS), a mechanism explaining the persistence of symptoms,
has been the focus of many research projects. Explanations given to patients with chronic …

Musculoskeletal pain is a condition that characterises several diseases and represents a
constantly growing issue with enormous socio-economic burdens, highlighting the …

Sensory perception and emotional disorders are disproportionally represented in men and
women and are thus thought to be modulated by different sex hormones in various …

Chronic musculoskeletal pain affects more than 20% of the population, leading to high
health care overload and huge spending. The prevalence is increasing and negatively …

Low back pain (LBP) is a leading cause of disability. It significantly impacts the patient's
quality of life, limits their daily living activities, and reduces their work productivity. To reduce …

Mechanosensory neurons that innervate the tongue provide essential information to guide
feeding, speech, and social grooming. We use in vivo calcium imaging of mouse trigeminal …

Pain is a complex multidimensional concept that facilitates the initiation of the signaling
cascade in response to any noxious stimuli. Action potential generation in the peripheral …

Fibromyalgia is a complex and heterogeneous clinical syndrome, mainly characterized by
the presence of widespread pain, possibly associated with a variety of other symptoms …

Maladaptation in sensory neural plasticity of nociceptive pathways is associated with various
types of chronic pain through central sensitization and remodeling of brain connectivity …

Somatosensation, the detection and transduction of external and internal stimuli such as
temperature or mechanical force, is vital to sustaining our bodily integrity. But still, some of …