How does cannabidiol (CBD) influence the acute effects of delta-9-tetrahydrocannabinol (THC) in humans? A systematic review

AM Freeman, K Petrilli, R Lees, C Hindocha… - Neuroscience & …, 2019 - Elsevier
The recent liberalisation of cannabis regulation has increased public and scientific debate
about its potential benefits and risks. A key focus has been the extent to which cannabidiol …

Systematic review of systematic reviews for medical cannabinoids: Pain, nausea and vomiting, spasticity, and harms

GM Allan, CR Finley, J Ton, D Perry, J Ramji… - Canadian Family …, 2018 - cfp.ca
Objective To determine the effects of medical cannabinoids on pain, spasticity, and nausea
and vomiting, and to identify adverse events. Data sources MEDLINE, the Cochrane …

'Standard THC units': a proposal to standardize dose across all cannabis products and methods of administration

TP Freeman, V Lorenzetti - Addiction, 2020 - Wiley Online Library
Abstract Background and Aims Cannabis products are becoming increasingly diverse, and
vary considerably in concentrations of∆ 9‐tetrahydrocannabinol (THC) and cannabidiol …

[HTML][HTML] Does cannabidiol make cannabis safer? A randomised, double-blind, cross-over trial of cannabis with four different CBD: THC ratios

A Englund, D Oliver, E Chesney, L Chester… - …, 2023 - nature.com
As countries adopt more permissive cannabis policies, it is increasingly important to identify
strategies that can reduce the harmful effects of cannabis use. This study aimed to determine …

Simplified guideline for prescribing medical cannabinoids in primary care

GM Allan, J Ramji, D Perry, J Ton, NP Beahm… - Canadian Family …, 2018 - cfp.ca
Objective To develop a clinical practice guideline for a simplified approach to medical
cannabinoid use in primary care; the focus was on primary care application, with a strong …

Cannabis use and the risk for psychosis and affective disorders

L Sideli, H Quigley, C La Cascia… - Journal of dual …, 2020 - Taylor & Francis
Objective: This review discusses the relationship between cannabis use and psychotic,
bipolar, depressive, and anxiety disorders, as well as suicide. It summarizes epidemiological …

[HTML][HTML] Individual and combined effects of acute delta-9-tetrahydrocannabinol and cannabidiol on psychotomimetic symptoms and memory function

CJA Morgan, TP Freeman, C Hindocha… - Translational …, 2018 - nature.com
The main active ingredient in cannabis, delta-9-tetrahydrocannabinol (THC), can acutely
induce psychotic symptoms and impair episodic and working memory. Another major …

Stages of dysfunctional decision-making in addiction

A Verdejo-Garcia, TTJ Chong, JC Stout, M Yücel… - Pharmacology …, 2018 - Elsevier
Drug use is a choice with immediate positive outcomes, but long-term negative
consequences. Thus, the repeated use of drugs in the face of negative consequences …

Cannabidiol reverses attentional bias to cigarette cues in a human experimental model of tobacco withdrawal

C Hindocha, TP Freeman, M Grabski, JB Stroud… - …, 2018 - Wiley Online Library
Abstract Background and Aims Cannabidiol (CBD), a non‐intoxicating cannabinoid found in
cannabis, may be a promising novel smoking cessation treatment due to its anxiolytic …

Acute memory and psychotomimetic effects of cannabis and tobacco both 'joint'and individually: a placebo-controlled trial

C Hindocha, TP Freeman, JX Xia… - Psychological …, 2017 - cambridge.org
BackgroundCannabis and tobacco have contrasting cognitive effects. Smoking cannabis
with tobacco is prevalent in many countries and although this may well influence cognitive …