Centrioles are conserved microtubule-based organelles that form the core of the centrosome
and act as templates for the formation of cilia and flagella. Centrioles have important roles in …

The centriole is an ancient microtubule-based organelle with a conserved nine-fold
symmetry. Centrioles form the core of centrosomes, which organize the interphase …

Primary cilia organize Hedgehog signaling and shape embryonic development, and their
dysregulation is the unifying cause of ciliopathies. We conducted a functional genomic …

Microtubules are cytoskeletal components involved in pivotal eukaryotic functions such as
cell division, ciliogenesis, and intracellular trafficking. They assemble from αβ-tubulin …

The centriole organelle consists of microtubules (MTs) that exhibit a striking 9-fold radial
symmetry. Centrioles play fundamental roles across eukaryotes, notably in cell signaling …

Microtubules are highly dynamic polymers of α, β-tubulin dimers which play an essential role
in numerous cellular processes such as cell proliferation and intracellular transport, making …

Primary cilia project from the surface of most vertebrate cells and are key in sensing
extracellular signals and locally transducing this information into a cellular response. Recent …

The centriole is a multifunctional structure that organizes centrosomes and cilia and is
important for cell signaling, cell cycle progression, polarity, and motility. Defects in centriole …

The centriole is a beautiful microtubule-based organelle that is critical for the proper
execution of many fundamental cellular processes, including polarity, motility, and division …

Centrioles play critical roles in organizing the assembly of the mitotic spindle and templating
the formation of primary cilia. Centriole duplication occurs once per cell cycle and is …