Ferroptosis is a programmed iron-dependent cell death characterized by accumulation of
lipid peroxides (LOOH) and redox disequilibrium. Ferroptosis shows unique characteristics …

Sirtuins (SIRTs) are a family of proteins with enzymatic activity. In particular, they are a family
of class III NAD+-dependent histone deacetylases and ADP-ribosyltransferases. NAD+ …

Doxorubicin (DOX) is an effective and widely used anticancer drug but has limited clinical
applicability because of its cardiotoxicity. Ferroptosis plays a key role in DOX-induced …

Oxidative stress, characterized by an imbalance favouring oxidants over antioxidants, is a
key contributor to the development of various common diseases. Counteracting these …

Neuropathic pain (NP) is the most prevalent and debilitating form of chronic pain, caused by
injuries or diseases of the somatosensory system. Since current first-line treatments only …

Mild cognitive impairment (MCI) and dementia are clinically prevalent in the elderly. There is
a high risk of cognitive decline in patients diagnosed with MCI or dementia. This review …

Abstract Oxidation resistance 1 (OXR1) is regarded as a critical regulator of cellular
homeostasis in response to oxidative stress. However, the role of OXR1 in the neuronal …

Viola stocksii Boiss. is an important medicinal food plant. The powdered form of the species
is mixed with butter and used as energy booster in subcontinent. The ethnomedicinal …

The control of neuropathic pain is a leading challenge in modern medicine. Traditional
medicine has, for a long time, used natural compounds such as nutraceuticals for this …

Neuropathic pain (NP) affects about 8% of the general population. Current analgesic
therapies have limited efficacy, making NP one of the most difficult to treat pain conditions …