Exploring the effects of Chinese herbal ingredients on the signaling pathway of alopecia and the screening of effective Chinese herbal compounds

Z Zhang, X Xu, X Zhang - Journal of Ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance alopecia is a hair disorder that can add a significant
medical and psychological burden to patients. Currently, the FDA-approved drugs for the …

Houttuynia Cordata Thunb.: A comprehensive review of traditional applications, phytochemistry, pharmacology and safety

P Wei, Q Luo, Y Hou, F Zhao, F Li, Q Meng - Phytomedicine, 2023 - Elsevier
Abstract Background Houttuynia Cordata Thunb.(H. cordata; Saururaceae) is a medicine
food homology plant that is grown in many Asian countries. Its main phytochemical …

Dexpanthenol promotes cell growth by preventing cell senescence and apoptosis in cultured human hair follicle cells

JY Shin, J Kim, YH Choi, NG Kang, S Lee - Current issues in molecular …, 2021 - mdpi.com
Dexpanthenol (D-panthenol) is a precursor of vitamin B5 (pantothenic acid) and is widely
used for dietary supplements and topical applications. D-panthenol has long been used in …

Hair growth-promoting effect of resveratrol in mice, human hair follicles and dermal papilla cells

Y Zhang, C Ni, Y Huang, Y Tang, K Yang… - Clinical, Cosmetic …, 2021 - Taylor & Francis
Background Oxidative damage has been found in various types of hair loss. As a
polyphenolic phytoalexin, resveratrol (RSV) is known as an antioxidant, anti-inflammatory …

Quercitrin stimulates hair growth with enhanced expression of growth factors via activation of MAPK/CREB signaling pathway

J Kim, SR Kim, YH Choi, JY Shin, CD Kim, NG Kang… - Molecules, 2020 - mdpi.com
The present study aimed to investigate the molecular mechanism of quercitrin, a major
constituent of Hottuynia cordata extract, for its hair growth stimulating activities in cultured …

Morus alba Root Extract Induces the Anagen Phase in the Human Hair Follicle Dermal Papilla Cells

J Hyun, J Im, SW Kim, HY Kim, I Seo, SH Bhang - Pharmaceutics, 2021 - mdpi.com
Restoring hair follicles by inducing the anagen phase is a promising approach to prevent
hair loss. Hair follicle dermal papilla cells (HFDPCs) play a major role in hair growth via the …

Anti-hair loss effect of adenosine is exerted by cAMP mediated wnt/β-catenin pathway stimulation via modulation of Gsk3β activity in cultured human dermal papilla …

J Kim, JY Shin, YH Choi, NG Kang, S Lee - Molecules, 2022 - mdpi.com
In the present study, we investigated the molecular mechanisms of adenosine for its hair
growth promoting effect. Adenosine stimulated the Wnt/β-catenin pathway by modulating the …

Effects of Baicalin on alopecia and the associated mechanism

L Chen, B Fan, H Gu, L Yang… - BioMed Research …, 2022 - Wiley Online Library
The aim of the present study was to explore the potential pharmacological mechanism of
baicalin by combining network pharmacology prediction and the experimental verification of …

Biotransformation of Cacumen platycladi Extract by Lactiplantibacillus plantarum CCFM1348 Promotes Hair Growth in Mice

X Tang, T Zhang, B Wang, B Mao… - Journal of Agricultural …, 2024 - ACS Publications
Cacumen platycladi (CP) is a frequently used traditional Chinese medicine to treat hair loss.
In this study, CP fermented by Lactiplantibacillus plantarum CCFM1348 increased the …

Hair growth promotion effect of nelumbinis semen extract with high antioxidant activity

HJ Park, GR Jin, JH Jung, SB Hwang… - Evidence‐Based …, 2021 - Wiley Online Library
This study investigated the hair regeneration promotion and hair loss prevention properties
of Nelumbinis Semen (NS) extract in vitro and in vivo. The effect of NS on the proliferation …