Sepsis is considered a major public health problem. Despite mortality being associated
consistently with organ compromise, the mechanisms by which sepsis causes multiple …

An understanding of the pathologic mechanisms of sepsis-induced AKI emphasizes the
important role of maladaptive responses to the septic insult. Preventive and therapeutic …

Introduction The role of systemic hemodynamics in the pathogenesis of septic acute kidney
injury (AKI) has received little attention. The purpose of this study was to investigate the …

The endothelial glycocalyx (EG) is the most luminal layer of the blood vessel, growing on
and within the vascular wall. It is mainly composed of a variety of proteoglycans and …

Renal replacement therapies (RRTs) represent a cornerstone in the management of severe
acute kidney injury. This area of intensive care and nephrology has undergone significant …

Cells of the innate and adaptive immune systems play a critical role in the host response to
sepsis. Moreover, their accessibility for sampling and their capacity to respond dynamically …

Background Due to the high incidence and mortality of sepsis-associated acute kidney
injury, a significant number of studies have explored the causes of sepsis-associated acute …

Background Severe sepsis is one of the leading causes of acute kidney injury (AKI). Patients
with sepsis‐associated AKI demonstrate high‐hospital mortality. We evaluated the incidence …

Introduction Sepsis is the leading cause of acute kidney injury (AKI) in critically ill patients.
The Kidney in Sepsis and Septic Shock (Kid-SSS) study evaluated the value of …

Sepsis is a common risk factor for acute kidney injury (AKI). Bone marrow-derived
mesenchymal stem cells (BMSCs) bear multi-directional differentiation potential. This study …