From femtoseconds to hours—measuring dynamics over 18 orders of magnitude with coherent x-rays

F Lehmkühler, W Roseker, G Grübel - Applied Sciences, 2021 - mdpi.com
X-ray photon correlation spectroscopy (XPCS) enables the study of sample dynamics
between micrometer and atomic length scales. As a coherent scattering technique, it …

A guide to sample delivery systems for serial crystallography

FZ Zhao, B Zhang, EK Yan, B Sun, ZJ Wang… - The FEBS …, 2019 - Wiley Online Library
Crystallography has made a notable contribution to our knowledge of structural biology. For
traditional crystallography experiments, the growth of crystals with large size and high …

Time-resolved serial femtosecond crystallography at the European XFEL

S Pandey, R Bean, T Sato, I Poudyal, J Bielecki… - Nature …, 2020 - nature.com
Abstract The European XFEL (EuXFEL) is a 3.4-km long X-ray source, which produces
femtosecond, ultrabrilliant and spatially coherent X-ray pulses at megahertz (MHz) repetition …

[PDF][PDF] Observation of substrate diffusion and ligand binding in enzyme crystals using high-repetition-rate mix-and-inject serial crystallography

S Pandey, G Calvey, AM Katz, TN Malla, FHM Koua… - IUCrJ, 2021 - journals.iucr.org
Here, we illustrate what happens inside the catalytic cleft of an enzyme when substrate or
ligand binds on single-millisecond timescales. The initial phase of the enzymatic cycle is …

Megahertz single-particle imaging at the European XFEL

E Sobolev, S Zolotarev, K Giewekemeyer… - Communications …, 2020 - nature.com
The emergence of high repetition-rate X-ray free-electron lasers (XFELs) powered by
superconducting accelerator technology enables the measurement of significantly more …

Emergence of anomalous dynamics in soft matter probed at the European XFEL

F Lehmkühler, F Dallari, A Jain… - Proceedings of the …, 2020 - National Acad Sciences
Dynamics and kinetics in soft matter physics, biology, and nanoscience frequently occur on
fast (sub) microsecond but not ultrafast timescales which are difficult to probe …

Membrane protein megahertz crystallography at the European XFEL

C Gisriel, J Coe, R Letrun, OM Yefanov… - Nature …, 2019 - nature.com
The world's first superconducting megahertz repetition rate hard X-ray free-electron laser
(XFEL), the European XFEL, began operation in 2017, featuring a unique pulse train …

Ultrafast X-ray photochemistry at European XFEL: capabilities of the femtosecond X-ray experiments (FXE) instrument

D Khakhulin, F Otte, M Biednov, C Bömer, TK Choi… - Applied Sciences, 2020 - mdpi.com
Featured Application Femtosecond X-ray Experiments on photoexcited chemical systems
deliver a portfolio of new observables including electronic, spin and nuclear dynamics. This …

[PDF][PDF] 3D printed devices and infrastructure for liquid sample delivery at the European XFEL

M Vakili, J Bielecki, J Knoška, F Otte… - Journal of …, 2022 - journals.iucr.org
The Sample Environment and Characterization (SEC) group of the European X-ray Free-
Electron Laser (EuXFEL) develops sample delivery systems for the various scientific …

[PDF][PDF] Microsecond hydrodynamic interactions in dense colloidal dispersions probed at the European XFEL

F Dallari, A Jain, M Sikorski, J Möller, R Bean… - IUCrJ, 2021 - journals.iucr.org
Many soft-matter systems are composed of macromolecules or nanoparticles suspended in
water. The characteristic times at intrinsic length scales of a few nanometres fall therefore in …