Biocatalysis, using enzymes for organic synthesis, has emerged as powerful tool for the
synthesis of active pharmaceutical ingredients (APIs). The first industrial biocatalytic …

Type 2 diabetes is a highly prevalent chronic metabolic disorder characterized by
hyperglycemia and associated with several complications such as retinopathy …

Background and aim Clinical evidence which investigated the effects of l-carnitine, a vitamin-
like substance, on weight loss had led to inconsistent results. This study therefore aimed to …

Despite preclinical studies demonstrating the efficacy of l-carnitine supplementation for
weight management, findings in clinical setting are contradictory. Electronic bibliographical …

Cellular metabolic changes during chronic kidney disease (CKD) may induce higher
production of oxygen radicals that play a significant role in the progression of renal damage …

Objective Inflammation mediators have been recognized as risk factors for the pathogenesis
of coronary artery disease (CAD). The purpose of this study was to investigate the effect of l …

Objective Several trials investigated the efficacy of L-carnitine administration on markers of
inflammation and indicators of oxidative stress; however, their findings are controversial. The …

Carnitine is a naturally occurring amino acid derivative that is involved in the transport of
long-chain fatty acids to the mitochondrial matrix. There, these substrates undergo β …

Background Sepsis, a life-threatening organ dysfunction caused by a host's dysregulated
response to infection with an inflammatory process, becomes a real challenge for the …

Background and aim l-carnitine has an important role in fatty acid metabolism and could
therefore act as an adjuvant agent in the improvement of dyslipidemia. The purpose of …