Pathological implication of protein post-translational modifications in cancer

S Pan, R Chen - Molecular aspects of medicine, 2022 - Elsevier
Protein post-translational modifications (PTMs) profoundly influence protein functions and
play crucial roles in essentially all cell biological processes. The diverse realm of PTMs and …

Advances in enrichment methods for mass spectrometry-based proteomics analysis of post-translational modifications

J Brandi, R Noberini, T Bonaldi, D Cecconi - Journal of Chromatography A, 2022 - Elsevier
Post-translational modifications (PTMs) occur during or after protein biosynthesis and
increase the functional diversity of proteome. They comprise phosphorylation, acetylation …

Proteomics of post-translational modifications in colorectal cancer: Discovery of new biomarkers

G Zhu, L Jin, W Sun, S Wang, N Liu - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
Colorectal cancer (CRC) is one of the costliest health problems and ranks second in cancer-
related mortality in developed countries. With the aid of proteomics, many protein …

Current trends in the analysis of post-translational modifications

D Virág, B Dalmadi-Kiss, K Vékey, L Drahos… - Chromatographia, 2020 - Springer
Post-translational modifications controlling a large number of biological functions are key
aspects of protein diversity. They have an important role controlling cellular processes and …

Bacterial endophytes: molecular interactions with their hosts

SS Dudeja, P Suneja‐Madan, M Paul… - Journal of Basic …, 2021 - Wiley Online Library
Plant growth promotion has been found associated with plants on the surface (epiphytic),
inside (endophytic), or close to the plant roots (rhizospheric). Endophytic bacteria mainly …

Current methods of post-translational modification analysis and their applications in blood cancers

K Dunphy, P Dowling, D Bazou, P O'Gorman - Cancers, 2021 - mdpi.com
Simple Summary This review discusses current techniques used to study post-translational
protein modifications (PTMs) and their contribution to blood cancer research. Blood cancer …

Orchestrating the proteome with post-translational modifications

SH Spoel - Journal of experimental botany, 2018 - academic.oup.com
4500| Special Issue Editorial fixed, dynamicity in proteome outputs is critical for responding
rapidly and efficiently to emerging threats. Protein phosphorylation is arguably the best …

What room for two-dimensional gel-based proteomics in a shotgun proteomics world?

K Marcus, C Lelong, T Rabilloud - Proteomes, 2020 - mdpi.com
Two-dimensional gel electrophoresis was instrumental in the birth of proteomics in the late
1980s. However, it is now often considered as an outdated technique for proteomics—a …

Posttranslational control of lipogenesis in the tumor microenvironment

Y Zhu, X Lin, X Zhou, EV Prochownik, F Wang… - Journal of Hematology & …, 2022 - Springer
Metabolic reprogramming of cancer cells within the tumor microenvironment typically occurs
in response to increased nutritional, translation and proliferative demands. Altered lipid …

Evaluation of the molecular mechanisms of sepsis using proteomics

H Miao, S Chen, R Ding - Frontiers in Immunology, 2021 - frontiersin.org
Sepsis is a complex syndrome promoted by pathogenic and host factors; it is characterized
by dysregulated host responses and multiple organ dysfunction, which can lead to death …