Drugs represent our first, and sometimes last, line of defense for many diseases, yet despite
decades of research we still do not fully understand why a given drug works in one patient …

Introduction The trillions of microorganisms that comprise the gut microbiome form dynamic
bidirectional interactions with orally administered drugs and host health. These relationships …

Drugs intended to target mammalian cells can have broad off‐target effects on the human
gut microbiota with potential downstream consequences for drug efficacy and side effect …

Gut dwelling microbes provide profound biochemical advantages to the host, including
nutrient and drug absorption, metabolism, and excretion. It is an emerging understanding …

Background Gliclazide, a second-generation sulfonylurea derivative still widely used as a
second-line treatment for type 2 diabetes mellitus, is well known to be subject to …

Background Acquiring sufficient knowledge and understanding the importance of intestinal
microbiota and probiotics in health and disease, as well as their potential for interactions …

Microorganisms have a close relationship with humans, whether it is commensal, symbiotic,
or pathogenic. Recently, it has been documented that microorganisms may influence the …

Drugs intended to target mammalian cells can have broad off-target effects on the human
gut microbiota with potential downstream consequences for drug efficacy and side effect …

Pharmacomicrobiomics: The universe of microbiome-drug interactions - Microbiome Times
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