Targeting dendritic cells to advance cross-presentation and vaccination outcomes
Dendritic cells (DCs) are a complex network of specialised antigen-presenting cells that are
critical initiators of adaptive immunity. Targeting antigen directly to DCs in situ is a …
critical initiators of adaptive immunity. Targeting antigen directly to DCs in situ is a …
Recombinant antigen delivery to dendritic cells as a way to improve vaccine design
GA de Souza-Silva, FB Sulczewski… - Experimental …, 2023 - journals.sagepub.com
Dendritic cells are central to the development of immunity, as they are specialized in
initiating antigen-specific immune responses. In this review, we briefly present the existing …
initiating antigen-specific immune responses. In this review, we briefly present the existing …
Interleukin-6 and indoleamine-2, 3-dioxygenase as potential adjuvant targets for Papillomavirus-related tumors immunotherapy
RL Pagni, PC Souza, R Pegoraro… - Frontiers in …, 2022 - frontiersin.org
High-risk Human papillomavirus (HPV) infections represent an important public health issue.
Nearly all cervical malignancies are associated with HPV, and a range of other female and …
Nearly all cervical malignancies are associated with HPV, and a range of other female and …
Transcriptional Targeting of Dendritic Cells Using an Optimized Human Fascin1 Gene Promoter
Y Zeyn, D Hobernik, U Wilk, J Pöhmerer… - International Journal of …, 2023 - mdpi.com
Deeper knowledge about the role of the tumor microenvironment (TME) in cancer
development and progression has resulted in new strategies such as gene-based cancer …
development and progression has resulted in new strategies such as gene-based cancer …
Oral Administration of Cancer Vaccines: Challenges and Future Perspectives
M Gambirasi, A Safa, I Vruzhaj, A Giacomin, F Sartor… - Vaccines, 2023 - mdpi.com
Cancer vaccines, a burgeoning strategy in cancer treatment, are exploring innovative
administration routes to enhance patient and medical staff experiences, as well as …
administration routes to enhance patient and medical staff experiences, as well as …
Governing HPV-related carcinoma using vaccines: Bottlenecks and breakthroughs
Human papillomavirus (HPV) contributes to sexually transmitted infection, which is primarily
associated with pre-cancerous and cancerous lesions in both men and women and is …
associated with pre-cancerous and cancerous lesions in both men and women and is …
FcRn regulates antigen presentation in dendritic cells downstream of DEC205-targeted vaccines
Dendritic cell (DC)-targeted vaccination is a new mode of antigen delivery that relies on the
use of monoclonal antibodies (mAb) to target antigen to specific DC subsets. The neonatal …
use of monoclonal antibodies (mAb) to target antigen to specific DC subsets. The neonatal …
Engineered Cancer Nanovaccines: A New Frontier in Cancer Therapy
Y Wang, C Liu, C Fang, Q Peng, W Qin, X Yan… - Nano-Micro Letters, 2025 - Springer
Vaccinations are essential for preventing and treating disease, especially cancer
nanovaccines, which have gained considerable interest recently for their strong anti-tumor …
nanovaccines, which have gained considerable interest recently for their strong anti-tumor …
Lymphatic distribution considerations for subunit vaccine design and development
PR Hartmeier, SM Ostrowski, EE Busch, KM Empey… - Vaccine, 2024 - Elsevier
Subunit vaccines are an important platform for controlling current and emerging infectious
diseases. The lymph nodes are the primary site generating the humoral response and …
diseases. The lymph nodes are the primary site generating the humoral response and …
Immune responses in oral papillomavirus clearance in the MmuPV1 mouse model
SA Brendle, JJ Li, V Walter, TD Schell, M Kozak… - Pathogens, 2023 - mdpi.com
Human papillomavirus (HPV)-induced oropharyngeal cancer now exceeds HPV-induced
cervical cancer, with a noticeable sex bias. Although it is well established that women have …
cervical cancer, with a noticeable sex bias. Although it is well established that women have …