Genetic and environmental risk factors for rheumatoid arthritis
KD Deane, MK Demoruelle, LB Kelmenson… - Best practice & research …, 2017 - Elsevier
Multiple genetic and environmental factors have been associated with an increased risk for
rheumatoid arthritis (RA). Of these, the strongest associations have been seen with female …
rheumatoid arthritis (RA). Of these, the strongest associations have been seen with female …
Neutrophil extracellular traps (NETs) in autoimmune diseases: a comprehensive review
KH Lee, A Kronbichler, DDY Park, YM Park, H Moon… - Autoimmunity …, 2017 - Elsevier
Neutrophil extracellular traps (NETs) are fibrous networks which protrude from the
membranes of activated neutrophils. NETs are found in a variety of conditions such as …
membranes of activated neutrophils. NETs are found in a variety of conditions such as …
Etiology and risk factors for rheumatoid arthritis: a state-of-the-art review
VC Romão, JE Fonseca - Frontiers in medicine, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is the most common systemic inflammatory rheumatic disease. It is
associated with significant burden at the patient and societal level. Extensive efforts have …
associated with significant burden at the patient and societal level. Extensive efforts have …
Interaction between the gut microbiome and mucosal immune system
N Shi, N Li, X Duan, H Niu - Military Medical Research, 2017 - Springer
The gut microbiota, the largest symbiotic ecosystem with the host, has been shown to play
important roles in maintaining intestinal homeostasis. Dysbiosis of the gut microbiome is …
important roles in maintaining intestinal homeostasis. Dysbiosis of the gut microbiome is …
Rheumatoid arthritis and the mucosal origins hypothesis: protection turns to destruction
VM Holers, MK Demoruelle, KA Kuhn… - Nature Reviews …, 2018 - nature.com
Individuals at high risk of developing seropositive rheumatoid arthritis (RA) can be identified
for translational research and disease prevention studies through the presence of highly …
for translational research and disease prevention studies through the presence of highly …
Oral mucosal breaks trigger anti-citrullinated bacterial and human protein antibody responses in rheumatoid arthritis
Periodontal disease is more common in individuals with rheumatoid arthritis (RA) who have
detectable anti-citrullinated protein antibodies (ACPAs), implicating oral mucosal …
detectable anti-citrullinated protein antibodies (ACPAs), implicating oral mucosal …
Periodontitis and rheumatoid arthritis: What have we learned about their connection and their treatment?
J González‐Febles, M Sanz - Periodontology 2000, 2021 - Wiley Online Library
Rheumatoid arthritis and periodontitis are chronic inflammatory diseases defined
respectively by the destruction of the articular cartilage and tooth‐supporting periodontal …
respectively by the destruction of the articular cartilage and tooth‐supporting periodontal …
NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis
R Khandpur, C Carmona-Rivera… - Science translational …, 2013 - science.org
The early events leading to the development of rheumatoid arthritis (RA) remain unclear, but
formation of autoantibodies to citrullinated protein antigens (ACPAs) is considered a key …
formation of autoantibodies to citrullinated protein antigens (ACPAs) is considered a key …
The pre-clinical phase of rheumatoid arthritis: from risk factors to prevention of arthritis
N Petrovská, K Prajzlerová, J Vencovský, L Šenolt… - Autoimmunity …, 2021 - Elsevier
Rheumatoid arthritis (RA) is a chronic autoimmune disease considered as a multistep
process spanning from the interaction of genetic (eg, shared epitope or non-HLA loci) …
process spanning from the interaction of genetic (eg, shared epitope or non-HLA loci) …
Periodontitis and Porphyromonas gingivalis in Patients With Rheumatoid Arthritis
Objective To examine the degree to which shared risk factors explain the relationship of
periodontitis (PD) to rheumatoid arthritis (RA) and to determine the associations of PD and …
periodontitis (PD) to rheumatoid arthritis (RA) and to determine the associations of PD and …