Antioxidant effects of N‐acetylcysteine on the male reproductive system: A systematic review

A Ghafarizadeh, M Malmir, S Naderi Noreini… - Andrologia, 2021 - Wiley Online Library
This study aimed to evaluate the effect of N‐acetyl cysteine on the male reproductive system
and consensus and classification of data found from previous studies. It is undeniable that N …

Radiation and male reproductive system: damage and protection

C Guo, Q Wang, P Shuai, T Wang, W Wu, Y Li… - Chemosphere, 2024 - Elsevier
Male fertility has been declining in recent decades, and a growing body of research points to
environmental and lifestyle factors as the cause. The widespread use of radiation …

Alpha-lipoic acid effectively attenuates ionizing radiation-mediated testicular dysfunction in rats: Crosstalk of NF-ĸB, TGF-β, and PPAR-ϒ pathways

RS Said, HA Mohamed, DH Kassem - Toxicology, 2020 - Elsevier
Radiotherapy is one of the principal approaches employed in the treatment of pelvic
cancers. Nevertheless, testicular dysfunction and infertility are among the most common …

Acetylated oligopeptide and n-acetyl cysteine protected against oxidative stress, inflammation, testicular-blood barrier damage, and testicular cell death in iron …

GM Ezzat, AY Nassar, MH Bakr, S Mohamed… - Applied Biochemistry …, 2023 - Springer
Multiple organs, including the testes, are damaged by iron overload. It has been shown that
N-acetyl cysteine (NAC) influences oxidative stress in iron overload. The present study …

The protective effects of angiotensin-converting enzyme inhibitor against cecal ligation and puncture-induced sepsis via oxidative stress and inflammation

U Kostakoglu, A Topcu, M Atak, L Tumkaya… - Life sciences, 2020 - Elsevier
Aims Sepsis is a severe public health problem affecting millions of individuals, with global
mortality rates caused by lower respiratory tract infections are approximately 2.38 million …

Radioprotective effects of α2-adrenergic receptor agonist dexmedetomidine on X-ray irradiation-induced pancreatic islet cell damage

F Mercantepe, L Tumkaya, T Mercantepe… - Naunyn-Schmiedeberg's …, 2023 - Springer
Comprehensive epidemiological analyses conducted in the last 30 years have revealed a
link between radiation and DM. We aimed to determine the effects of dexmedetomidine …

Ameliorative effect of N‐acetylcysteine on the testicular tissue of adult male albino rats after glyphosate‐based herbicide exposure

AR Hashim, DW Bashir, NAE Yasin… - … of Biochemical and …, 2022 - Wiley Online Library
Glyphosate (GLP) is a broad‐spectrum herbicide that is frequently used in crop production,
but its residues remain in foodstuffs. This, in turn, has led to potential adverse effects on both …

Wuzi-Yanzong prescription alleviates spermatogenesis disorder induced by heat stress dependent on Akt, NF-κB signaling pathway

SQ Hu, DL Liu, CR Li, YH Xu, K Hu, LD Cui, J Guo - Scientific Reports, 2021 - nature.com
Akt and nuclear factor kappa B (NF-κB) signaling pathways are involved in germ cell
apoptosis and inflammation after testicular heat stress (THS). We observed that after THS …

The radioprotective effect of N-acetylcysteine against x-radiation-induced renal injury in rats

T Mercantepe, A Topcu, S Rakici, L Tumkaya… - … Science and Pollution …, 2019 - Springer
The purpose of this study was therefore to investigate the effects of radiotherapy on the
kidney and the potential use of agents such as N-acetylcysteine (NAC) in developing a …

An investigation of the effects of metformin on ovarian ischemia-reperfusion injury in rats

A Topcu, G Balik, M Atak, T Mercantepe… - European journal of …, 2019 - Elsevier
Damage to the ovaries or tissue torsion can significantly reduce the ovarian reserve and
thus cause severe gynecological and hormonal deficiencies. The discovery of new agents is …