Although much progress is being made in understanding the molecular pathways in the
placenta that are involved in the pathophysiology of pregnancy-related disorders, a …

Increasing maternal mortality and incidence of arrhythmias in pregnancy have been noted
over the past 2 decades in the United States. Pregnancy is associated with a greater risk of …

The antiphospholipid syndrome (APS) is characterized by recurrent fetal loss, intrauterine
growth restriction, and vascular thrombosis in the presence of antiphospholipid (aPL) Abs …

Background Pre-eclampsia, a pregnancy-specific multisystemic disorder is a leading cause
of maternal and perinatal mortality and morbidity. This syndrome has been known to medical …

Pre‐eclampsia is a potentially life‐threatening disease of women during pregnancy leading
to hypertension and proteinuria. It affects 1 in 15 pregnancies but, despite intense research …

Introduction: Preeclampsia is one of the major causes of maternal and neonatal mortality.
During pregnancy, the immune system must maintain the tolerance to the fetus, thus …

Specific inhibitors of COX-2 have been associated with increased risk for cardiovascular
complications. These agents reduce prostacyclin (PGI 2) without affecting production of …

Preeclampsia affects up to 8% of pregnancies worldwide and is a leading cause of both
maternal and fetal morbidity and mortality. Our current understanding of the cause (s) of …

Mice are widely used to study arterial disease in humans, and the pathogenesis of arterial
diseases is known to be strongly influenced by hemodynamic factors. It is, therefore, of …

Over the past decade, non-invasive preclinical imaging has emerged as an important tool to
facilitate biomedical discovery. Not only have the markets for these tools accelerated, but the …