Silicon-stereogenic chiral organosilanes have found increasing applications in synthetic
chemistry, medicinal chemistry, and materials science. In this context, various asymmetric …

Asymmetric organocatalysis has experienced a long and spectacular way since the early
reports over a century ago by von Liebig, Knoevenagel and Bredig, showing that small …

Spirooxindoles have emerged as promising architectures for engineering biologically active
compounds. The diastereodivergent construction of unique scaffolds of this type with full …

Summary Asymmetric coupling of 1, 3-dienes with carbonyl compounds is one of the most
powerful tools for atom-economical construction of the Csp 3–Csp 3 bond. Although many …

The creation of full stereoisomers of an organic compound comprising multiple contiguous
stereocenters with simultaneous control over both relative and absolute configurations …

As a fundamental and synthetically useful C− C bond formation reaction, the aldol reaction is
one of the most versatile transformations in organic synthesis. However, despite extensive …

Desymmetrization is an essential method for the synthesis of chiral compounds, particularly
chiral biaryls. We have developed an enantioselective synthesis of axially chiral biaryls by …

From its beginnings in the Sonogashira reaction, synergistic dual transition-metal catalysis
has gained increasing prominence and importance. In the past decade, this strategy has …

Creating, conserving and modifying the stereochemistry of organic compounds has been the
subject of significant research efforts in synthetic chemistry. Most synthetic routes are …

Covalent organic frameworks (COFs) have undergone extensive research as
heterogeneous catalysts for a wide range of significant reactions, but they have not yet been …