Pathogenicity islands in bacterial pathogenesis
H Schmidt, M Hensel - Clinical microbiology reviews, 2004 - Am Soc Microbiol
In this review, we focus on a group of mobile genetic elements designated pathogenicity
islands (PAI). These elements play a pivotal role in the virulence of bacterial pathogens of …
islands (PAI). These elements play a pivotal role in the virulence of bacterial pathogens of …
Functions of the Salmonella pathogenicity island 2 (SPI-2) type III secretion system effectors
R Figueira, DW Holden - Microbiology, 2012 - microbiologyresearch.org
Salmonella enterica serovars cause severe disease in humans, such as gastroenteritis and
typhoid fever. The bacteria are able to invade and replicate within host cells, including …
typhoid fever. The bacteria are able to invade and replicate within host cells, including …
Salmonellae interplay with host cells
A Haraga, MB Ohlson, SI Miller - Nature Reviews Microbiology, 2008 - nature.com
Salmonellae are important causes of enteric diseases in all vertebrates. Characterization of
the molecular mechanisms that underpin the interactions of salmonellae with their animal …
the molecular mechanisms that underpin the interactions of salmonellae with their animal …
Type III secretion systems and disease
Type III secretion systems (T3SSs) are complex bacterial structures that provide gram-
negative pathogens with a unique virulence mechanism enabling them to inject bacterial …
negative pathogens with a unique virulence mechanism enabling them to inject bacterial …
The Salmonella-containing vacuole—moving with the times
O Steele-Mortimer - Current opinion in microbiology, 2008 - Elsevier
Salmonella pathogenesis is dependent on its ability to invade and replicate within host cells.
Following invasion the bacteria remain within a modified phagosome known as the …
Following invasion the bacteria remain within a modified phagosome known as the …
Functions and effectors of the Salmonella pathogenicity island 2 type III secretion system
SR Waterman, DW Holden - Cellular microbiology, 2003 - Wiley Online Library
Salmonella enterica uses two functionally distinct type III secretion systems encoded on the
pathogenicity islands SPI‐1 and SPI‐2 to transfer effector proteins into host cells. A major …
pathogenicity islands SPI‐1 and SPI‐2 to transfer effector proteins into host cells. A major …
Salmonella effector SopB reorganizes cytoskeletal vimentin to maintain replication vacuoles for efficient infection
S Zhao, Q Xu, Y Cui, S Yao, S Jin, Q Zhang… - Nature …, 2023 - nature.com
A variety of intracellular bacteria modulate the host cytoskeleton to establish subcellular
niches for replication. However, the role of intermediate filaments, which are crucial for …
niches for replication. However, the role of intermediate filaments, which are crucial for …
Salmonella effectors: important players modulating host cell function during infection
TA Agbor, BA McCormick - Cellular microbiology, 2011 - Wiley Online Library
Salmonella enterica serovar Typhimurium (S. Typhimurium) is a Gram‐negative facultative
food‐borne pathogen that causes gastroenteritis in humans. This bacterium has evolved a …
food‐borne pathogen that causes gastroenteritis in humans. This bacterium has evolved a …
The PhoP/PhoQ system controls the intramacrophage type three secretion system of Salmonella enterica
JJE Bijlsma, EA Groisman - Molecular microbiology, 2005 - Wiley Online Library
Spi/Ssa is a unique type three secretion system that functions exclusively when Salmonella
enterica is inside eukaryotic cells. Expression of the Spi/Ssa system and its secreted …
enterica is inside eukaryotic cells. Expression of the Spi/Ssa system and its secreted …
SpvC is a Salmonella effector with phosphothreonine lyase activity on host mitogen‐activated protein kinases
P Mazurkiewicz, J Thomas, JA Thompson… - Molecular …, 2008 - Wiley Online Library
SpvC is encoded by the Salmonella virulence plasmid. We have investigated the
biochemical function of SpvC and the mechanism by which it is secreted by bacteria and …
biochemical function of SpvC and the mechanism by which it is secreted by bacteria and …