Staphylococcus aureus is one of the most common pathogens of humans and animals,
where it frequently colonizes skin and mucosal membranes. It is of major clinical importance …

Endolysins and their derivatives have emerged in recent years as a novel class of
antibacterials, which have now entered the clinical phases. Their rapid mode-of-action and …

Phage therapy, the use of bacteriophages (phages) to treat bacterial infections, is regaining
momentum as a promising weapon against the rising threat of multidrug-resistant (MDR) …

Local delivery of antimicrobials for otitis media treatment would maximize therapeutic
efficacy while minimizing side effects. However, drug transport across the tympanic …

The resurgence of research into phage biology and therapy is, in part, due to the increasing
need for novel agents to treat multidrug-resistant infections. Despite a long clinical history in …

Orthopaedic device-related infection (ODRI) presents a significant challenge to the field of
orthopaedic and trauma surgery. Despite extensive treatment involving surgical …

Urinary catheters have been used on an intermittent or indwelling basis for centuries, in
order to relieve urinary retention and incontinence. Nevertheless, the use of urinary …

Ability to efficiently propagate high quantities of bacteriophages (phages) is of great
importance considering higher phage production needs in the future. Continuous production …

For centuries, mankind is dealing with deadly infectious diseases. Broad-spectrum
antibiotics are commonly used against these bacterial infections. However, due to the …

Antibiotics are the most successful intervention of mankind. Millions of lives have been
saved by antibiotics. These are powerful drugs in the medicine history. Antibiotics are …