The diterpenoids present highly varied oxidation patterns subjected to fascinating skeletal
rearrangements, and possess antitumor, antibacterial, antihyperglycemic, anti-inflammatory …

Bone remodelling is generally a dynamic process orchestrated by bone-resorbing
osteoclasts and bone-forming osteoblasts. Osteoclasts are the only cell type capable of …

Background. The consumption of sweeteners has increased in recent years, being used to
control body weight and blood glucose. However, they can cause increased appetite …

Stevioside, a natural glycoside compound, has many beneficial biological activities, but its
protective effect on myocardial fibrosis has not been reported yet. This study aimed to …

Crystallization has revolutionized the field of solid-state formulations by modulating the
physiochemical and release profile of active pharmaceutical ingredients (APIs). Dimethyl …

Nanoparticles (NPs), having exceptional physicochemical and electrical characteristics with
lower toxicity, have evolved as dynamic drug delivery carriers in living organisms …

Background Terpenoids, present in essential oils (EOs), have gained significant attention
due to their diverse pharmacological properties and their alignment with the growing global …

Objective The aim of this work was to explore the possible protective effects and its
mechanism of stevioside on cerebral ischemia reperfusion (CIR) induced neuron damages …

Background Compared with steviol glycosides, the taste of glucosylated steviol glycosides is
better and more similar to that of sucrose. At present, cyclodextrin glucanotransferase …

Aseptic loosening and periprosthetic osteolysis are the leading causes of total joint
arthroplasty failure, which occurs as a result of chronic inflammatory response and …