How do we improve patient compliance and adherence to long-term statin therapy?

P Maningat, BR Gordon, JL Breslow - Current atherosclerosis reports, 2013 - Springer
Statins are highly effective drugs prescribed to millions of people to lower LDL-cholesterol
and decrease cardiovascular risk. The benefits of statin therapy seen in randomized clinical …

Interventions to improve adherence to lipid‐lowering medication

ML van Driel, MD Morledge, R Ulep… - Cochrane Database …, 2016 - cochranelibrary.com
Background Lipid‐lowering drugs are widely underused, despite strong evidence indicating
they improve cardiovascular end points. Poor patient adherence to a medication regimen …

Nonadherence to statins: individualized intervention strategies outside the pill box

P Lansberg, A Lee, ZV Lee… - Vascular health and …, 2018 - Taylor & Francis
Poor adherence to statin therapy is linked to significantly increased risk of cardiovascular
events and death. Unfortunately, adherence to statins is far from optimal. This is an alarming …

Low-density lipoprotein receptor genotype and response to pravastatin in children with familial hypercholesterolemia: substudy of an intima-media thickness trial

KCMC Koeijvoets, J Rodenburg, BA Hutten… - Circulation, 2005 - Am Heart Assoc
Background—The lipid-lowering effects of statin therapy show considerable interindividual
variation in patients with familial hypercholesterolemia (FH). Whether the type of LDL …

[图书][B] Statin Prescribing in Australian and Irish General Practice: A Qualitative Study

BD Montgomery - 2012 - research-repository.uwa.edu.au
Background: The prevention and treatment of cardiovascular disease is a challenge for
health systems internationally. Statins (HMG-CoA reductase inhibitors) are widely …

Analisi dei fattori di rischio per la non-aderenza ai programmi terapeutici nel paziente con patologia cardiovascolare cronica complessa

K Stellato - 2018 - arts.units.it
Background Oltre 4 milioni di persone muoiono ogni anno in Europa di malattie
cardiovascolari (CV) e 1.4 milioni di questi decessi avvengono prima dei 75 anni di età …

[PDF][PDF] Kristel CMC Koeijvoets, Jessica Rodenburg, Barbara A. Hutten, Albert

JJP Wiegman, EJG Sijbrands - Complex Genetics of Monogenic Familial …, 2005 - core.ac.uk
Background: The lipid lowering effects of statin therapy show considerable interindividual
variation in patients with familial hypercholesterolemia (FH). Whether or not the type of …

[PDF][PDF] Ewout W. Steyerberg, Joep C. Defesche, John JP Kastelein, MD, Steven WJ Lamberts, and Eric JG Sijbrands

KCMC Koeijvoets, JB van der Net… - Complex Genetics of …, 2006 - repub.eur.nl
Context: Individuals with the functional ER22/23EK variant in the glucocorticoid receptor
gene are relatively resistant to the downstream consequences of glucocorticoids. Evidence …