Metabolic pathway analysis using stable isotopes in patients with cancer

CR Bartman, B Faubert, JD Rabinowitz… - Nature Reviews …, 2023 - nature.com
Metabolic reprogramming is central to malignant transformation and cancer cell growth. How
tumours use nutrients and the relative rates of reprogrammed pathways are areas of intense …

[HTML][HTML] The age-related loss of skeletal muscle mass and function: Measurement and physiology of muscle fibre atrophy and muscle fibre loss in humans

DJ Wilkinson, M Piasecki, PJ Atherton - Ageing research reviews, 2018 - Elsevier
Age-related loss of skeletal muscle mass and function, sarcopenia, is associated with
physical frailty and increased risk of morbidity (chronic diseases), in addition to all-cause …

[图书][B] Amino acids: biochemistry and nutrition

G Wu - 2021 - taylorfrancis.com
Following its predecessor, the second edition of Amino Acids: Biochemistry and Nutrition
presents exhaustive coverage of amino acids in the nutrition, metabolism and health of …

Proteome turnover in the spotlight: approaches, applications, and perspectives

AB Ross, JD Langer, M Jovanovic - Molecular & Cellular Proteomics, 2021 - ASBMB
In all cells, proteins are continuously synthesized and degraded to maintain protein
homeostasis and modify gene expression levels in response to stimuli. Collectively, the …

Spatial multiplexing and omics

JL Carstens, SN Krishnan, A Rao, AG Sorace… - Nature Reviews …, 2024 - nature.com
Much like solving a game of Clue, understanding physiological mysteries involves
answering who, what, when and where. Multiomics approaches delve into cellular and …

Quantifying label enrichment from two mass isotopomers increases proteome coverage for in vivo protein turnover using heavy water metabolic labeling

HM Deberneh, DR Abdelrahman, SK Verma… - Communications …, 2023 - nature.com
Heavy water metabolic labeling followed by liquid chromatography coupled with mass
spectrometry is a powerful high throughput technique for measuring the turnover rates of …

Tendon extracellular matrix assembly, maintenance and dysregulation throughout life

SM Siadat, DE Zamboulis, CT Thorpe… - Progress in Heritable …, 2021 - Springer
Abstract In his Lissner Award medal lecture in 2000, Stephen Cowin asked the
question:“How is a tissue built?” It is not a new question, but it remains as relevant today as it …

Advances of stable isotope technology in food safety analysis and nutrient metabolism research

W Xia, X Fang, Y Gao, W Wu, Y Han, R Liu, H Yang… - Food Chemistry, 2023 - Elsevier
Food quality, safety, and the regulatory metabolism of food nutrients in cells are primary
factors in determining human health. However, residues of undesirable or hazardous …

13C tracer analysis suggests extensive recycling of endogenous CO2 in vivo

L Duan, DE Cooper, G Scheidemantle… - Cancer & …, 2022 - Springer
Background 13C tracer analysis is increasingly used to monitor cellular metabolism in vivo
and in intact cells, but data interpretation is still the key element to unveil the complexity of …

Understanding HDL metabolism and biology through in vivo tracer kinetics

AB Andraski, FM Sacks, M Aikawa… - … , and Vascular Biology, 2024 - Am Heart Assoc
HDL (high-density lipoprotein), owing to its high protein content and small size, is the
densest circulating lipoprotein. In contrast to lipid-laden VLDL (very-low-density lipoprotein) …