Maternal immune activation and neuroinflammation in human neurodevelopmental disorders

VX Han, S Patel, HF Jones, RC Dale - Nature Reviews Neurology, 2021 - nature.com
Maternal health during pregnancy plays a major role in shaping health and disease risks in
the offspring. The maternal immune activation hypothesis proposes that inflammatory …

[HTML][HTML] Innate immune dysfunction and neuroinflammation in autism spectrum disorder (ASD)

HK Hughes, RJ Moreno, P Ashwood - Brain, behavior, and immunity, 2023 - Elsevier
Autism spectrum disorder (ASD) is a highly heterogeneous neurodevelopmental disorder
characterized by communication and social behavior deficits. The presence of restricted and …

[HTML][HTML] Neuroinflammation and oxidative stress in the pathogenesis of autism spectrum disorder

N Usui, H Kobayashi, S Shimada - International Journal of Molecular …, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder (NDD) characterized by
impairments in social communication, repetitive behaviors, restricted interests, and …

[HTML][HTML] IL-6 and IL-8: an overview of their roles in healthy and pathological pregnancies

A Vilotić, M Nacka-Aleksić, A Pirković… - International journal of …, 2022 - mdpi.com
Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic action,
mediating innate and adaptive immunity and multiple physiological processes, including …

Maternal anxiety, depression and stress affects offspring gut microbiome diversity and bifidobacterial abundances

JD Galley, L Mashburn-Warren, LC Blalock… - Brain, Behavior, and …, 2023 - Elsevier
Uncovering mechanisms underlying fetal programming during pregnancy is of critical
importance. Atypical neurodevelopment during the pre-and immediate postnatal period has …

[HTML][HTML] The impact of maternal high-fat diet on offspring neurodevelopment

G Urbonaite, A Knyzeliene, FS Bunn… - Frontiers in …, 2022 - frontiersin.org
A maternal high-fat diet affects offspring neurodevelopment with long-term consequences on
their brain health and behavior. During the past three decades, obesity has rapidly …

[HTML][HTML] A review on the vagus nerve and autonomic nervous system during fetal development: searching for critical windows

F Cerritelli, MG Frasch, MC Antonelli… - Frontiers in …, 2021 - frontiersin.org
The autonomic nervous system (ANS) is one of the main biological systems that regulates
the body's physiology. Autonomic nervous system regulatory capacity begins before birth as …

[HTML][HTML] Microbiota and microglia interactions in ASD

M Davoli-Ferreira, CA Thomson, KD McCoy - Frontiers in immunology, 2021 - frontiersin.org
Autism spectrum disorders (ASD) are serious, highly variable neurodevelopmental
disorders, commonly characterized by the manifestation of specific behavioral abnormalities …

[HTML][HTML] Inflammation, anxiety, and stress in attention-deficit/hyperactivity disorder

LF Saccaro, Z Schilliger, N Perroud, C Piguet - Biomedicines, 2021 - mdpi.com
Attention-deficit/hyperactivity disorder (ADHD) is a prevalent and serious
neurodevelopmental disorder characterized by symptoms of inattention and/or hyperactivity …

[HTML][HTML] The impact of maternal diabetes on the future health and neurodevelopment of the offspring: a review of the evidence

K Rodolaki, V Pergialiotis, N Iakovidou… - Frontiers in …, 2023 - frontiersin.org
Maternal health during gestational period is undoubtedly critical in shaping optimal fetal
development and future health of the offspring. Gestational diabetes mellitus is a metabolic …