In situ-forming injectable hydrogels are smart biomaterials that can be implanted into living
bodies with minimal invasion. Due to pioneer work of Prof. Sung Wan Kim in this field …

Hydrogels are cross-linked hydrophilic macromolecules that contain a certain amount of
water. Due to their biocompatible, highly tunable and hydrophilic nature, hydrogels have …

Highlights•Hydrogel-based drug delivery systems can be more efficacious than the systemic
therapies.•They provide a high concentration and a sustained release of the drugs at tumor …

Stimuli-sensitive injectable polymeric hydrogels have been extensively investigated during
the past decade as bioactive agent delivery vehicles and for tissue engineering applications …

Since drug delivery systems have become one of the most promising areas of human health
related research, the applications of biomaterials such as hydrogels have been widely …

Injectable hydrogels are a unique class of hydrogels that are formed upon injection into
living bodies. They possess features of typical hydrogels such as softness, 3D network …

Hydrogels are physically and chemically cross-linked, 3D, porous, hydrated molecular
structures that mimic the native tissue microenvironment. Hydrogels fabricated with …

Polymer hydrogels have been widely explored as therapeutic delivery matrices because of
their ability to present sustained, localized and controlled release of bioactive factors …

In the past two decades, physical polymeric hydrogels have been extensively explored for
biomedical applications, such as drug delivery and tissue engineering. These hydrogels …

This study is aimed to develop a long-acting injectable formulation in treatment of type II
diabetes. A glucoregulatory polypeptide, exenatide (EXT), was chosen as the model drug …