Nanopore: Emerging for detecting protein post-translational modifications
X Zhao, H Qin, M Tang, X Zhang, G Qing - TrAC Trends in Analytical …, 2024 - Elsevier
Protein post-translational modifications (PTMs) play pivotal roles in almost every cellular
process, influencing protein stability, localization, interactions, and enzymatic activities. PTM …
process, influencing protein stability, localization, interactions, and enzymatic activities. PTM …
Atomistic simulation of molecules interacting with biological nanopores: from current understanding to future directions
A Acharya, JD Prajapati… - The Journal of Physical …, 2022 - ACS Publications
Biological nanopores have been at the focus of numerous studies due to their role in many
biological processes as well as their (prospective) technological applications. Among many …
biological processes as well as their (prospective) technological applications. Among many …
Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel
Abstract Connexin 36 (Cx36) is responsible for signal transmission in electrical synapses by
forming interneuronal gap junctions. Despite the critical role of Cx36 in normal brain …
forming interneuronal gap junctions. Despite the critical role of Cx36 in normal brain …
Direct single-molecule detection of CoA-SH and ATP by the membrane proteins TMEM120A and TMEM120B
C Zhao, M Chen, X Liu, W Yuan, K Li, Y Wang, C Chen… - Nanoscale, 2024 - pubs.rsc.org
Membrane proteins are vital resources for developing biosensors. TMEM120A is a
membrane protein associated with human pain transmission and lipid metabolism, and …
membrane protein associated with human pain transmission and lipid metabolism, and …
Recent advances of nanopore-based analysis for carbohydrate and glycoconjugate
Saccharides are not only the basic constituents and nutrients of living organisms, but also
participate in various life activities, and play important roles in cell recognition, immune …
participate in various life activities, and play important roles in cell recognition, immune …
Conformational flexibility driving charge-selective substrate translocation across a bacterial transporter
D Vikraman, BB Majumdar, SK Sharavanakkumar… - Chemical …, 2024 - pubs.rsc.org
Bacterial membrane porins facilitate the translocation of small molecules while restricting
large molecules, and this mechanism remains elusive at the molecular level. Here, we …
large molecules, and this mechanism remains elusive at the molecular level. Here, we …
[HTML][HTML] Importance of the lysine cluster in the translocation of anions through the pyrophosphate specific channel OprO
Pseudomonas aeruginosa is a Gram-negative bacterium with an intrinsic resistance towards
antibiotics due to the lack of a large diffusion pores. Exchange of substances with the …
antibiotics due to the lack of a large diffusion pores. Exchange of substances with the …
Biphasic concentration patterns in ionic transport under nanoconfinement revealed in steady state and time-dependent properties
M Queralt-Martin, JJ Pérez-Grau, LMA González… - Biophysical …, 2023 - cell.com
Monday, February 20, 2023 223a geometry and chemistry and also the nature of the ionic
solution flowing through it. Accordingly, the concentration at which a given property will …
solution flowing through it. Accordingly, the concentration at which a given property will …
Translocation of ssDNA through charged graphene nanopores: effect of the charge density
YS Zhang, ZY Qi, MM Ding, ML Li, TF Shi - Chinese Journal of Polymer …, 2024 - Springer
Nanopore sequencing harnesses changes in ionic current as nucleotides traverse a
nanopore, enabling real-time decoding of DNA/RNA sequences. The instruments for the …
nanopore, enabling real-time decoding of DNA/RNA sequences. The instruments for the …