Charging and supercharging of proteins for mass spectrometry: recent insights into the mechanisms of electrospray ionization

L Konermann, H Metwally, Q Duez, I Peters - Analyst, 2019 - pubs.rsc.org
Electrospray ionization (ESI) is an essential technique for transferring proteins from solution
into the gas phase for mass spectrometry and ion mobility spectrometry. The mechanisms …

Capillary electrophoresis–electrospray ionization-mass spectrometry interfaces: Fundamental concepts and technical developments

G Bonvin, J Schappler, S Rudaz - Journal of Chromatography A, 2012 - Elsevier
Capillary electrophoresis (CE) hyphenated to electrospray ionization (ESI) mass
spectrometry (MS) is a powerful tool for analyzing a wide variety of analytes in different …

Ion mobilities in diatomic gases: measurement versus prediction with non-specular scattering models

C Larriba, CJ Hogan Jr - The Journal of Physical Chemistry A, 2013 - ACS Publications
Ion/electrical mobility measurements of nanoparticles and polyatomic ions are typically
linked to particle/ion physical properties through either application of the Stokes–Millikan …

Modeling the behavior of coarse-grained polymer chains in charged water droplets: implications for the mechanism of electrospray ionization

E Ahadi, L Konermann - The Journal of Physical Chemistry B, 2012 - ACS Publications
The mechanism whereby macromolecular analytes are transferred into the gas phase
during the final stages of electrospray ionization (ESI) remains a matter of debate. In this …

Formation of gaseous proteins via the ion evaporation model (IEM) in electrospray mass spectrometry

E Aliyari, L Konermann - Analytical chemistry, 2020 - ACS Publications
The mechanisms whereby protein ions are released into the gas phase from charged
droplets during electrospray ionization (ESI) continue to be controversial. Several pathways …

Formation of Gaseous Peptide Ions from Electrospray Droplets: Competition between the Ion Evaporation Mechanism and Charged Residue Mechanism

E Aliyari, L Konermann - Analytical chemistry, 2022 - ACS Publications
The transfer of peptide ions from solution into the gas phase by electrospray ionization (ESI)
is an integral component of mass spectrometry (MS)-based proteomics. The mechanisms …

Release of nanodiscs from charged nano-droplets in the electrospray ionization revealed by molecular dynamics simulations

B Wang, DP Tieleman - Communications Chemistry, 2023 - nature.com
Electrospray ionization (ESI) is essential for application of mass spectrometry in biological
systems, as it prevents the analyte being split into fragments. However, due to lack of a clear …

Atomistic modeling of jet formation in charged droplets

S Consta - The Journal of Physical Chemistry B, 2022 - ACS Publications
The first atomistic simulations that reveal the mechanism of Rayleigh fission are presented. It
is demonstrated that simple ion or macroion ejection takes place through droplet …

[HTML][HTML] The properties of the polyethylene glycol complex PEG (Na+)(Cu+) on the copper electrodeposited layer by Time-of-Flight Secondary-Ion Mass Spectrometry …

R Mroczka, A Słodkowska - Electrochimica Acta, 2020 - Elsevier
The properties of polyethylene glycol PEG (Na+)(Cu+) complex on the copper
electrodeposition layer was studied by Time-of-Flight Secondary-Ion Mass Spectrometry …

Release mechanisms of poly (ethylene glycol) macroions from aqueous charged nanodroplets

JK Chung, S Consta - The Journal of Physical Chemistry B, 2012 - ACS Publications
Ion-release processes in nanodroplets that contain excess charge are of central importance
in atmospheric aerosols as well as in determining the charge state distributions of macroions …