[HTML][HTML] Stabilizing vaccines via drying: Quality by design considerations
Z Ghaemmaghamian, R Zarghami, G Walker… - Advanced Drug Delivery …, 2022 - Elsevier
Pandemics and epidemics are continually challenging human beings' health and imposing
major stresses on the societies particularly over the last few decades, when their frequency …
major stresses on the societies particularly over the last few decades, when their frequency …
Premix technologies for drug delivery: manufacturing, applications, and opportunities in regulatory filing
Active pharmaceutical ingredients (APIs) and excipients can be carefully combined in
premix-based materials before being added to dosage forms, providing a flexible platform …
premix-based materials before being added to dosage forms, providing a flexible platform …
[HTML][HTML] Production, physicochemical investigations, antioxidant effect, and cellular uptake in Caco-2 cells of the supersaturable astaxanthin self-microemulsifying …
WT Aung, HEE Khine, C Chaotham… - European Journal of …, 2022 - Elsevier
The purpose of this study was to develop astaxanthin (AST)-loaded self-microemulsifying
drug delivery system (SMEDDS) tablets and evaluate their physicochemical and biological …
drug delivery system (SMEDDS) tablets and evaluate their physicochemical and biological …
A new parameter for characterization of tablet friability based on a systematical study of five excipients
H Zhao, Y Yu, N Ni, L Zhao, X Lin, Y Wang, R Du… - International Journal of …, 2022 - Elsevier
In this paper, a new parameter highly relevant to tablet friability is proposed based on a
systematical study of the tablet quality attributes and texture performances of five different …
systematical study of the tablet quality attributes and texture performances of five different …
Drying behaviour and visualization of surfactants after co-spray drying of surfactant-stabilized aqueous suspensions
E De Pauw, Y Chen, H De Keersmaecker… - International Journal of …, 2023 - Elsevier
Surfactants are widely used in many industries as dispersants or flocculants for
suspensions. As the addition of low concentrations of surfactant is sufficient to execute their …
suspensions. As the addition of low concentrations of surfactant is sufficient to execute their …
Predicting spray dried dispersion particle size via machine learning regression methods
JM Schmitt, JM Baumann, MM Morgen - Pharmaceutical Research, 2022 - Springer
Spray dried dispersion particle size is a critical quality attribute that impacts bioavailability
and manufacturability of the spray drying process and final dosage form. Substantial …
and manufacturability of the spray drying process and final dosage form. Substantial …
Formation of delta-mannitol by co-spray drying: enhancing the tabletability of paracetamol/mannitol formulations
E De Pauw, C Vervaet, V Vanhoorne - Journal of Drug Delivery Science …, 2022 - Elsevier
Abstract δ-mannitol is a metastable polymorph of mannitol, known for its superior tableting
properties. However, there is no easy, reproducible and scalable production method for δ …
properties. However, there is no easy, reproducible and scalable production method for δ …
Comparative direct compression property of a novel pregelatinized starch in paracetamol tablets
T Balcha Balla, N Mary Joseph… - … in Pharmacological and …, 2023 - Wiley Online Library
Background. Among all the pharmaceutical dosage forms, tablets are still the most preferred
and the most commonly used option because of their advantages. The direct compression …
and the most commonly used option because of their advantages. The direct compression …
Optimization of Pregelatinized Taro Boloso‐I Starch as a Direct Compression Tablet Excipient
TB Balla, NM Joseph, A Belete - BioMed Research International, 2023 - Wiley Online Library
Background. Tablets are still the most preferred means of drug delivery. The search for new
and improved direct compression tablet excipients is an area of research focus. This is …
and improved direct compression tablet excipients is an area of research focus. This is …
Transdermal delivery of pramipexole using microneedle technology for the potential treatment of Parkinson's disease
MB McGuckin, ARJ Hutton, ER Davis… - Molecular …, 2024 - ACS Publications
Parkinson's disease (PD) is a debilitating neurodegenerative disease primarily impacting
neurons responsible for dopamine production within the brain. Pramipexole (PRA) is a …
neurons responsible for dopamine production within the brain. Pramipexole (PRA) is a …