Abstract The usage of Peptide-Based Drug-delivery systems (PBDs) is a strategy in which
peptides carry a variety of compounds with pharmacological activity into cells. These …

Cytotoxic peptides derived from spider venoms have been considered as promising
candidates for anticancer treatment. The novel cell penetrating peptide LVTX-8, which is a …

MicroRNAs (miRNAs) are post-transcriptional gene expression regulators with potential
therapeutic applications. miR-146a is a negative regulator of inflammatory processes in both …

The development of new antibiotics is urgently required because of the rapidly growing
resistance against conventional antibiotics. The antimicrobial peptides show potential as …

Extracellular synthetic nucleic acids, such as siRNAs, are unable to reach their intended
targets efficiently. Therefore, delivery methods such as cell-penetrating peptides (CPP) …

Glycoconjugation is a promising modification strategy for the optimization of peptide drugs.
In this study, five different monosaccharide derivatives (7a–e) were covalently linked to the N …

Non-viral gene delivery systems have gained considerable attention as a promising
alternative to viral delivery to treat diseases associated with aberrant gene expression …

The successful application of gene therapy relies on the development of safe and efficient
delivery vectors. Cationic polymers such as cell-penetrating peptides (CPPs) can condense …

A new family of cyclic cell‐penetrating peptides (CPPs) has been discovered; they differ from
previously reported cyclic CPPs by containing only a single hydrophobic residue. The …

With the advent of cancer immunotherapy, immunomodulation has emerged as an important
strategy for the treatment of various diseases. We review recent advances in clinical trials of …