Despite acknowledgement in the scientific community of sex-based differences in cartilage
biology, the implications for study design remain unclear, with many studies continuing to …

Osteoarthritis is the most prevalent arthritis typically characterized by degradation of
cartilage. However, its pathogenesis is not fully understood. Currently, osteoarthritis is best …

Cartilage lesions in degenerative osteoarthritis (OA) are involved with pathological
microenvironmental alterations induced by inflammatory macrophages, and apoptotic and/or …

In vivo articular cartilage degeneration is an essential hallmark of osteoarthritis (OA),
involving chondrocyte senescence, extracellular matrix degradation, chondrocyte death …

The potential biological function of tea and its active components on colitis has attracted
wide attention. In this study, different tea active ingredients including tea polyphenols …

Circular RNAs (circRNAs), a class of non-coding RNAs (ncRNAs), are highly stable and
ubiquitous molecules that exhibit tissue-specific expression. Accumulating evidence has …

Articular cartilage damage and chondrocyte apoptosis are common features of rheumatoid
arthritis and osteoarthritis. Recently, curcumin has been reported to exhibit protective effects …

Rheumatoid arthritis is a common autoimmune disease that results from the deposition of
antibodies–autoantigens in the joints, leading to long-lasting inflammation. The main …

Rationale: Synovial inflammation is one of the main pathological features of rheumatoid
arthritis (RA) and is a key factor leading to the progression of RA. Understanding the …

Acid-sensing ion channel 1a (ASIC1a) is a member of the extracellular H+-activated cation
channel family. Emerging evidence has suggested that ASIC1a plays a crucial role in the …