The physics of proton therapy

WD Newhauser, R Zhang - Physics in Medicine & Biology, 2015 - iopscience.iop.org
The physics of proton therapy has advanced considerably since it was proposed in 1946.
Today analytical equations and numerical simulation methods are available to predict and …

Range uncertainties in proton therapy and the role of Monte Carlo simulations

H Paganetti - Physics in Medicine & Biology, 2012 - iopscience.iop.org
The main advantages of proton therapy are the reduced total energy deposited in the patient
as compared to photon techniques and the finite range of the proton beam. The latter adds …

Nuclear physics in particle therapy: a review

M Durante, H Paganetti - Reports on Progress in Physics, 2016 - iopscience.iop.org
Charged particle therapy has been largely driven and influenced by nuclear physics. The
increase in energy deposition density along the ion path in the body allows reducing the …

A review of the use and potential of the GATE Monte Carlo simulation code for radiation therapy and dosimetry applications

D Sarrut, M Bardiès, N Boussion, N Freud… - Medical …, 2014 - Wiley Online Library
In this paper, the authors' review the applicability of the open‐source GATE Monte Carlo
simulation platform based on the GEANT4 toolkit for radiation therapy and dosimetry …

[图书][B] Proton therapy physics

H Paganetti - 2018 - books.google.com
Expanding on the highly successful first edition, this second edition of Proton Therapy
Physics has been completely restructured and updated throughout, and includes several …

A potential revolution in cancer treatment: A topical review of FLASH radiotherapy

Y Gao, R Liu, CW Chang, S Charyyev… - Journal of Applied …, 2022 - Wiley Online Library
FLASH radiotherapy (RT) is a novel technique in which the ultrahigh dose rate (UHDR)(≥
40 Gy/s) is delivered to the entire treatment volume. Recent outcomes of in vivo studies …

Reducing the sensitivity of IMPT treatment plans to setup errors and range uncertainties via probabilistic treatment planning

J Unkelbach, T Bortfeld, BC Martin… - Medical physics, 2009 - Wiley Online Library
Treatment plans optimized for intensity modulated proton therapy (IMPT) may be very
sensitive to setup errors and range uncertainties. If these errors are not accounted for during …

Dose calculation algorithms for external radiation therapy: an overview for practitioners

F De Martino, S Clemente, C Graeff, G Palma, L Cella - Applied sciences, 2021 - mdpi.com
Featured Application Radiation therapy treatment planning. Abstract Radiation therapy (RT)
is a constantly evolving therapeutic technique; improvements are continuously being …

Dosimetric evaluation of a commercial proton spot scanning Monte-Carlo dose algorithm: comparisons against measurements and simulations

J Saini, D Maes, A Egan, SR Bowen… - Physics in Medicine …, 2017 - iopscience.iop.org
Abstract RaySearch Americas Inc.(NY) has introduced a commercial Monte Carlo dose
algorithm (RS-MC) for routine clinical use in proton spot scanning. In this report, we provide …

Elevated LET components in clinical proton beams

C Grassberger, H Paganetti - Physics in Medicine & Biology, 2011 - iopscience.iop.org
This paper assesses the contribution of secondary particles to pencil and passively
scattered proton beams, in particular when considering the dose-averaged linear energy …