Role of turmeric and curcumin in prevention and treatment of chronic diseases: Lessons learned from clinical trials

AB Kunnumakkara, M Hegde, D Parama… - ACS Pharmacology & …, 2023 - ACS Publications
Turmeric (Curcuma longa) has been used for thousands of years for the prevention and
treatment of various chronic diseases. Curcumin is just one of> 200 ingredients in turmeric …

The mechanism of hyperglycemia-induced renal cell injury in diabetic nephropathy disease: an update

T Wu, L Ding, V Andoh, J Zhang, L Chen - Life, 2023 - mdpi.com
Diabetic Nephropathy (DN) is a serious complication of type I and II diabetes. It develops
from the initial microproteinuria to end-stage renal failure. The main initiator for DN is chronic …

Systemic immune-inflammation index is associated with diabetic kidney disease in Type 2 diabetes mellitus patients: Evidence from NHANES 2011-2018

W Guo, Y Song, Y Sun, H Du, Y Cai, Q You… - Frontiers in …, 2022 - frontiersin.org
Objective Diabetic kidney disease (DKD) is the most common chronic kidney disease (CKD)
and has the highest prevalence of end-stage kidney disease (ESKD) globally, owing mostly …

[HTML][HTML] Podocyte-specific Nlrp3 inflammasome activation promotes diabetic kidney disease

K Shahzad, S Fatima, H Khawaja, A Elwakiel, I Gadi… - Kidney International, 2022 - Elsevier
Efficient therapies for diabetic kidney disease (DKD), now the leading cause of kidney
failure, are lacking. One hallmark of DKD is sterile inflammation (inflammation in absence of …

New strategies to improve clinical outcomes for diabetic kidney disease

T Forst, C Mathieu, F Giorgino, DC Wheeler… - Bmc Medicine, 2022 - Springer
Background Diabetic kidney disease (DKD), the most common cause of kidney failure and
end-stage kidney disease worldwide, will develop in almost half of all people with type 2 …

Cellular senescence and regulated cell death of tubular epithelial cells in diabetic kidney disease

S Shen, C Ji, K Wei - Frontiers in Endocrinology, 2022 - frontiersin.org
Cellular senescence is frequently evident at etiologic sites of chronic diseases and involves
essentially irreversible arrest of cell proliferation, increased protein production, resistance to …

[HTML][HTML] Diabetic nephropathy–a review of risk factors, progression, mechanism, and dietary management

V Natesan, SJ Kim - Biomolecules & therapeutics, 2021 - ncbi.nlm.nih.gov
Type 2 diabetes mellitus (T2DM) leads to many health problems like diabetic nephropathy
(DN). One of the key factors for chronic kidney disease and end-stage renal disease (ESRD) …

Mitochondria in diabetic kidney disease

AA Ahmad, SO Draves, M Rosca - Cells, 2021 - mdpi.com
Diabetic kidney disease (DKD) is the leading cause of end stage renal disease (ESRD) in
the USA. The pathogenesis of DKD is multifactorial and involves activation of multiple …

Prevention of microvascular complications of diabetes

W Crasto, V Patel, MJ Davies… - … and Metabolism Clinics, 2021 - endo.theclinics.com
Global prevalence estimates from 2019 suggest that the number of people diagnosed with
diabetes was 463 million and is projected to increase to 700 million by the year 2045. 1 The …

Vitamin D and diabetic kidney disease

HY Huang, TW Lin, ZX Hong, LM Lim - International Journal of Molecular …, 2023 - mdpi.com
Vitamin D is a hormone involved in many physiological processes. Its active form, 1, 25 (OH)
2D3, modulates serum calcium–phosphate homeostasis and skeletal homeostasis. A …