Sporadically advocated over the last two centuries, a cerebellar role in cognition and affect
has been rigorously established in the past few decades. In the clinical domain, such …

Alzheimer's disease (AD) is a heterogeneous progressive neurocognitive disorder. Although
different neuroimaging modalities have been used for the identification of early diagnostic …

Objective The purpose of this study was to identify subtypes of amyotrophic lateral sclerosis
(ALS) by comparing patterns of neurodegeneration using brain magnetic resonance …

Just as the epigenome, the proteome and the electrophysiological properties of a cell
influence its function, so too do its intrinsic mechanical properties and its extrinsic …

Parkinson disease (PD) is characterized by heterogeneous motor and non-motor symptoms,
resulting from neurodegeneration involving various parts of the central nervous system …

Treadmill training (TT) has been extensively used as an intervention to improve gait and
mobility in patients with Parkinson's disease (PD). Regional and global effects on brain …

Introduction Semantic dementia, including the semantic variant of primary progressive
aphasia (svPPA), is strongly associated with TAR-DNA binding protein 43 (TDP-43) type C …

The γ-aminobutyric acid (GABA) ergic system is the primary inhibitory neurotransmission
system in the mammalian brain. Its dysregulation has been shown in multiple brain …

The continuous adherence to the conventional “one target, one drug” paradigm has failed so
far to provide effective therapeutic solutions for heterogeneous and multifactorial diseases …

Age-related decline in cognitive functions and dementia are major challenges in geriatric
healthcare. Accumulating evidence from clinical, epidemiological and animal research …