Telomere length: how the length makes a difference
M Lulkiewicz, J Bajsert, P Kopczynski… - Molecular Biology …, 2020 - Springer
Telomerase is perceived as an immortality enzyme that might provide longevity to cells and
whole organisms. Importantly, it is generally inactive in most somatic cells of healthy, adult …
whole organisms. Importantly, it is generally inactive in most somatic cells of healthy, adult …
[HTML][HTML] Effect of aging on behaviour of mesenchymal stem cells
JA Fafián-Labora, M Morente-López… - World Journal of Stem …, 2019 - ncbi.nlm.nih.gov
Organs whose source is the mesoderm lineage contain a subpopulation of stem cells that
are able to differentiate among mesodermal derivatives (chondrocytes, osteocytes …
are able to differentiate among mesodermal derivatives (chondrocytes, osteocytes …
Melatonin plays critical role in mesenchymal stem cell-based regenerative medicine in vitro and in vivo
C Hu, L Li - Stem cell research & therapy, 2019 - Springer
Although stem cells have emerged as promising sources for regenerative medicine, there
are many potential safety hazards for their clinical application, including tumorigenicity, an …
are many potential safety hazards for their clinical application, including tumorigenicity, an …
Cytokines secreted from bone marrow derived mesenchymal stem cells promote apoptosis and change cell cycle distribution of K562 cell line as clinical agent in cell …
Mesenchymal stem cells (MSCs) are of special interest due their potential clinical use in cell-
based therapy. Therapies engaging MSCs are showing increasing promise in the cancer …
based therapy. Therapies engaging MSCs are showing increasing promise in the cancer …
METTL3-mediated m6A modification regulates cell cycle progression of dental pulp stem cells
H Luo, W Liu, Y Zhang, Y Yang, X Jiang, S Wu… - Stem cell research & …, 2021 - Springer
Background Dental pulp stem cells (DPSCs) are a promising cell source in endodontic
regeneration and tissue engineering with limited self-renewal and pluripotency capacity. N 6 …
regeneration and tissue engineering with limited self-renewal and pluripotency capacity. N 6 …
Mesenchymal stem cells in acute myeloid leukemia: a focus on mechanisms involved and therapeutic concepts
Drug resistance in cancer, especially in leukemia, creates a dilemma in treatment planning.
Consequently, studies related to the mechanisms underlying drug resistance, the molecular …
Consequently, studies related to the mechanisms underlying drug resistance, the molecular …
[HTML][HTML] DNA methylation modulates aging process in adipocytes
H Xie, X Liu, Q Zhou, T Huang, L Zhang, J Gao… - Aging and …, 2022 - ncbi.nlm.nih.gov
Aging has been recognized to be a highly complex biological health problem with a high risk
of chronic diseases, including type 2 diabetes, atherosclerosis, chronic bronchitis or …
of chronic diseases, including type 2 diabetes, atherosclerosis, chronic bronchitis or …
Mesenchymal stem cells pretreated with collagen promote skin wound-healing
Z Kou, B Li, A Aierken, N Tan, C Li, M Han… - International Journal of …, 2023 - mdpi.com
The existing treatment modalities for skin injuries mainly include dressings, negative-
pressure wound treatment, autologous skin grafting, and high-pressure wound treatment. All …
pressure wound treatment, autologous skin grafting, and high-pressure wound treatment. All …
The nutraceutical value of carnitine and its use in dietary supplements
A Durazzo, M Lucarini, A Nazhand, SB Souto, AM Silva… - Molecules, 2020 - mdpi.com
Carnitine can be considered a conditionally essential nutrient for its importance in human
physiology. This paper provides an updated picture of the main features of carnitine …
physiology. This paper provides an updated picture of the main features of carnitine …
[HTML][HTML] Interleukin-6,-8, and TGF-β secreted from mesenchymal stem cells show functional role in reduction of telomerase activity of leukemia cell via Wnt5a/β-catenin …
Purpose: The effect of mesenchymal stem cells (MSCs) on the immortality features of
malignant cells, such as hematologic cancerous cells, are controversial, and the associated …
malignant cells, such as hematologic cancerous cells, are controversial, and the associated …