Telomerase is perceived as an immortality enzyme that might provide longevity to cells and
whole organisms. Importantly, it is generally inactive in most somatic cells of healthy, adult …

Organs whose source is the mesoderm lineage contain a subpopulation of stem cells that
are able to differentiate among mesodermal derivatives (chondrocytes, osteocytes …

Although stem cells have emerged as promising sources for regenerative medicine, there
are many potential safety hazards for their clinical application, including tumorigenicity, an …

Mesenchymal stem cells (MSCs) are of special interest due their potential clinical use in cell-
based therapy. Therapies engaging MSCs are showing increasing promise in the cancer …

Background Dental pulp stem cells (DPSCs) are a promising cell source in endodontic
regeneration and tissue engineering with limited self-renewal and pluripotency capacity. N 6 …

Drug resistance in cancer, especially in leukemia, creates a dilemma in treatment planning.
Consequently, studies related to the mechanisms underlying drug resistance, the molecular …

Aging has been recognized to be a highly complex biological health problem with a high risk
of chronic diseases, including type 2 diabetes, atherosclerosis, chronic bronchitis or …

The existing treatment modalities for skin injuries mainly include dressings, negative-
pressure wound treatment, autologous skin grafting, and high-pressure wound treatment. All …

Carnitine can be considered a conditionally essential nutrient for its importance in human
physiology. This paper provides an updated picture of the main features of carnitine …

Purpose: The effect of mesenchymal stem cells (MSCs) on the immortality features of
malignant cells, such as hematologic cancerous cells, are controversial, and the associated …