The correlation between epigenetics and human reproduction represents a very interesting
field of study, mainly due to the possible transgenerational effects related to epigenetic …

Infertility is considered a major public health issue, and approximately 1 out of 6 people
worldwide suffer from infertility during their reproductive lifespans. Thanks to technological …

Cytogenetic and molecular deletion analyses of azoospermic and oligozoospermic males
have suggested the existence of AZoospermia Factor (s)(AZF) residing in deletion intervals …

In this study the substantial and in part contradictory data available in the literature was
collected concerning the frequency of small supernumerary marker chromosomes (sSMC) in …

The heterogeneity of the protocols employed and of the results published, together with the
increasing diffusion of this diagnostic procedure, suggested the necessity of a quality control …

Infertility–the inability to achieve conception or sustain a pregnancy through to live birth–is
very common and affects about 15% of couples. While chromosomal or genetic …

Background There have been reports suggesting that children born after in-vitro fertilisation
by intracytoplasmic sperm injection (ICSI) are at increased risk of neurodevelopmental …

Spermatogenesis is an essential reproductive process that is regulated by many Y
chromosome specific genes. Most of these genes are located in a specific region known as …

Recent discoveries of many new genes have made it clear that there is more to the human Y
chromosome than a heap of evolutionary debris, hooked up to a sequence that happens to …

The introduction of ICSI and testicular sperm extraction (TESE) has allowed many infertile
men to father children. The biggest concern about the wide use of these techniques is the …