The CB 2 receptor is the peripheral receptor for cannabinoids. It is mainly expressed in
immune tissues, highlighting the possibility that the endocannabinoid system has an …

Arachidonoyl-glycerol (2-AG) and arachidonyl-ethanolamide (AEA) are endocannabinoids
that have been implicated in many physiologic disorders, including obesity, metabolic …

Asthma is characterized by chronic lung inflammation and airway hyperresponsiveness.
Asthma remains a major public health problem and, at present, there are no effective …

The immune system can be modulated and regulated not only by foreign antigens but also
by other humoral factors and metabolic products, which are able to affect several …

Abstract The endocannabinoids 2-arachidonoyl-glycerol (2-AG) and N-arachidonoyl-
ethanolamine (AEA) are eicosanoids implicated in numerous physiological processes like …

The cannabinoid CB2 receptor was cloned from the promyeloid cell line HL-60 and is
notably expressed in most, if not all leukocyte types. This relatively restricted localization …

Sepsis, defined as the dysregulated immune response to an infection leading to organ
dysfunction, is one of the leading causes of mortality around the globe. Despite the …

The definition of asthma has changed considerably in recent years, to the extent that asthma
is no longer considered a single disease but a heterogeneous disorder that includes several …

Eosinophils have been linked with asthma for more than a century, but their role has been
unclear. This review discusses the roles of eosinophils in asthma and chronic obstructive …

From their phylogenetic and pharmacological classification it might be inferred that
cannabinoid receptors and their endogenous ligands constitute a rather specialised and …