[HTML][HTML] Cerebral small vessel disease in sporadic and familial Alzheimer disease

RN Kalaria, D Sepulveda-Falla - The American journal of pathology, 2021 - Elsevier
Alzheimer disease (AD) is the most common cause of dementia. Biological definitions of AD
are limited to the cerebral burden of amyloid β plaques, neurofibrillary pathology, and …

[HTML][HTML] Diabetes and cognitive function: An evidence-based current perspective

MJ Sebastian, SKA Khan, JM Pappachan… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Several epidemiological studies have clearly identified diabetes mellitus (DM) as a major
risk factor for cognitive dysfunction, and it is going to be a major public health issue in the …

[HTML][HTML] Future directions for dementia risk reduction and prevention research: an international research network on dementia prevention consensus

KJ Anstey, R Peters, L Zheng… - Journal of …, 2020 - content.iospress.com
In the past decade a large body of evidence has accumulated on risk factors for dementia,
primarily from Europe and North America. Drawing on recent integrative reviews and a …

Sudden cardiac death in synucleinopathies

K Javanshiri, T Drakenberg, M Haglund… - … of Neuropathology & …, 2023 - academic.oup.com
The purpose of this study was to investigate the cause of death in subjects with α-
synucleinopathies (ASs) and the confirmed presence of cardiac α-synuclein (α-syn) …

[HTML][HTML] Acute Myocardial Infarction and Risk of Cognitive Impairment and Dementia: A Review

EHE Thong, EJW Quek, JH Loo, CY Yun, YN Teo… - Biology, 2023 - mdpi.com
Simple Summary Cognitive impairment (CI) and dementia are common in patients with heart
attacks, and both share common cardiovascular risk factors. In our ageing population, the …

Association of vascular and degenerative brain pathologies and past medical history from the National Alzheimer's Coordinating Center Database

KA Scambray, HL Nguyen… - Journal of Neuropathology …, 2023 - academic.oup.com
The relationship between past medical histories (PMH) and dementia-related
neuropathologies is not well understood. Using the National Alzheimer's Coordinating …

[HTML][HTML] Investigation of hypertension and type 2 diabetes as risk factors for dementia in the All of Us cohort

SD Nagar, P Pemu, J Qian, E Boerwinkle, M Cicek… - Scientific reports, 2022 - nature.com
Abstract The World Health Organization recently defined hypertension and type 2 diabetes
(T2D) as modifiable comorbidities leading to dementia and Alzheimer's disease. In the …

Natural edible materials made of protein-functionalized aerogel particles for postprandial hyperglycemia management

L Guo, J Xia, S Yu, J Yan, F He, M Zhang, Q Fan… - International Journal of …, 2021 - Elsevier
Abstract α-Amylase inhibitors (α-AIs) delay digestion of dietary starch by inhibiting α-
amylase in the gut, thereby reducing the postprandial glycemia, which is beneficial to the …

[HTML][HTML] Essential New Complex-Based Themes for Patient-Centered Diagnosis and Treatment of Dementia and Predementia in Older People: Multimorbidity and …

E Wertman - Journal of Clinical Medicine, 2024 - mdpi.com
Dementia is a highly prevalent condition with devastating clinical and socioeconomic
sequela. It is expected to triple in prevalence by 2050. No treatment is currently known to be …

Cardiovascular Disease and Dementia: Exploring Intersections, Risks, and Therapeutic Challenges

L Huang, J Meir, WH Frishman… - Cardiology in Review, 2024 - journals.lww.com
This review examines the complex bidirectional relationship between cardiovascular
disease and various dementia subtypes, including Alzheimer's disease, vascular dementia …