Targeting the renin–angiotensin–aldosterone system to prevent hypertension and kidney disease of developmental origins

CN Hsu, YL Tain - International Journal of Molecular Sciences, 2021 - mdpi.com
The renin-angiotensin-aldosterone system (RAAS) is implicated in hypertension and kidney
disease. The developing kidney can be programmed by various early-life insults by so …

The AGE-RAGE Axis and the Pathophysiology of Multimorbidity in COPD

NL Reynaert, LEGW Vanfleteren… - Journal of Clinical …, 2023 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is a disease of the airways and lungs due to
an enhanced inflammatory response, commonly caused by cigarette smoking. Patients with …

Consensus-based recommendations on priority activities to address acute kidney injury in children: a modified Delphi consensus statement

SL Goldstein, A Akcan-Arikan, R Alobaidi… - JAMA network …, 2022 - jamanetwork.com
Importance Increasing evidence indicates that acute kidney injury (AKI) occurs frequently in
children and young adults and is associated with poor short-term and long-term outcomes …

Contemporary perspectives in COPD: patient burden, the role of gender and trajectories of multimorbidity

SC Buttery, M Zysman, SAA Vikjord… - …, 2021 - Wiley Online Library
An individual's experience of COPD is determined by many factors in addition to the
pathological features of chronic bronchitis and emphysema and the symptoms that derive …

[HTML][HTML] Obesity and chronic kidney disease: prevalence, mechanism, and management

HE Yim, KH Yoo - Clinical and Experimental Pediatrics, 2021 - ncbi.nlm.nih.gov
The prevalence of childhood obesity is increasing worldwide at an alarming rate. While
obesity is known to increase a variety of cardiovascular and metabolic diseases, it also acts …

Childhood risk factors for adulthood chronic kidney disease

M Stern-Zimmer, R Calderon-Margalit, K Skorecki… - Pediatric …, 2021 - Springer
Chronic kidney disease (CKD) is a major public health challenge, affecting as much as 8 to
18% of the world population. Identifying childhood risk factors for future CKD may help …

Gestational systolic blood pressure trajectories and risk of adverse maternal and perinatal outcomes in Chinese women

H Teng, Y Wang, B Han, J Liu, Y Cao, J Wang… - BMC Pregnancy and …, 2021 - Springer
Background Associations between trajectories of systolic blood pressure (SBP) during
pregnancy and pregnant outcomes remain unclear and disparate. Methods Data of 20,353 …

Effects of prematurity on long-term renal health: a systematic review

A Sangla, Y Kandasamy - BMJ open, 2021 - bmjopen.bmj.com
Objective To investigate the literature and determine if prematurity has an impact on long-
term adverse kidney outcomes. Design Systematic review. Data sources OVID Medline …

Advances and potential of regenerative medicine in pediatric nephrology

GG Slaats, J Chen, E Levtchenko, MC Verhaar… - Pediatric …, 2024 - Springer
The endogenous capacity of the kidney to repair is limited, and generation of new nephrons
after injury for adequate function recovery remains a need. Discovery of factors that promote …

Systemic hypertension in infants with bronchopulmonary dysplasia

MC Starr, AC Wilson - Current Hypertension Reports, 2022 - Springer
Abstract Purpose of Review Neonatal hypertension is increasingly recognized as
improvements in neonatal intensive care have led to increased survival of premature infants …