Schizophrenia is a disorder with a heterogeneous etiology involving complex interplay
between genetic and environmental risk factors. The immune system is now known to play …

Schizophrenia is a severe psychiatric disorder with high heritability. Consortia efforts and
technological advancements have led to a substantial increase in knowledge of the genetic …

Schizophrenia is a complex and often chronic psychiatric disorder with high heritability.
Diagnosis of schizophrenia is still made clinically based on psychiatric symptoms; no …

Abstract Machine learning (ML) holds promise for precision psychiatry, but its predictive
performance is unclear. We assessed whether ML provided added value over logistic …

Schizophrenia is a major psychotic disorder with multifactorial etiology that includes
interactions between genetic vulnerability and environmental risk factors. In addition …

Pre-clinical models, postmortem and neuroimaging studies all support a role for muscarinic
receptors in the molecular pathology of schizophrenia. From these data it was proposed that …

Genome-wide association studies (GWASs) have detected many susceptible variants for
common diseases, including psychiatric disorders. However, because of the small effect size …

Background Psychiatric disorders have seriously affected human life, one of the risk genes
related to psychosis is the methylenetetrahydrofolatereductase (MTHFR) gene. This gene …

Brain aging, which involves a progressive loss of neuronal functions, has been reported to
be premature in probands affected by schizophrenia (SCZ). Evidence shows that SCZ and …

Schizophrenia is a heterogeneous psychiatric disorder with a strong genetic basis, whose
etiology and pathophysiology remain poorly understood. Exome sequencing studies have …