Advances and challenges in modeling inherited peripheral neuropathies using iPSCs

J Van Lent, R Prior, G Pérez Siles, AN Cutrupi… - … & Molecular Medicine, 2024 - nature.com
Inherited peripheral neuropathies (IPNs) are a group of diseases associated with mutations
in various genes with fundamental roles in the development and function of peripheral …

Therapeutic indications for HDAC6 inhibitors in the peripheral and central nervous disorders

J van Eyll, R Prior, S Celanire… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Inhibition of the enzymatic function of HDAC6 is currently being explored in
clinical trials ranging from peripheral neuropathies to cancers. Advances in selective …

The Effects of Reduced Glial Plasma Membrane Cholesterol on Actin Dynamics: Insights into Neuropathic Mechanisms

RK Athira - 2024 - search.proquest.com
Demyelinating neuropathy, a neurological disorder characterized by progressive loss of
myelin, leads to impaired nerve function and sensory deficits. A cure or disease-modifying …