The gold drugs, gold sodium thiomalate (Myocrisin), aurothioglucose (Solganal), and the
orally administered auranofin (Ridaura), are utilized in modern medicine for the treatment of …

Candida albicans is the most common human fungal pathogen, causing infections that
range from mucous membranes to systemic infections. The present article provides an …

Extracellular matrixes (ECMs), such as the cell walls and biofilms, are important for
supporting cell integrity and function and regulating intercellular communication. These …

The prevalence of fungal infections is growing at an alarming pace and the pathogenesis is
still not clearly understood. Recurrence of these fungal diseases is often due to their …

The development of antimicrobial drug resistance among pathogenic bacteria and fungi is
one of the most significant health issues of the 21st century. Recently, advances in …

Many short cationic peptides are amphiphilic and are often termed antimicrobial peptides
(AMPs) as they can kill various microorganisms. These AMPs have largely been discovered …

Infectious keratitis is a significant cause of corneal blindness worldwide. Although less
prevalent in the developed world, cases of fungal keratitis account for almost half of all …

The indole scaffold is found in a wide range of bioactive heterocycles and natural products.
Moreover, the indole moiety is considered as the active principle in several alkaloids such …

Candida albicans is the most common human fungal pathogen causing diseases ranging
from mucosal to systemic infections. As a commensal, C. albicans asymptomatically …

The high mortality of invasive fungal infections, and the limited number and inefficacy of
antifungals necessitate the development of new agents with novel mechanisms and targets …