NAFLD and increased risk of cardiovascular disease: clinical associations, pathophysiological mechanisms and pharmacological implications

G Targher, CD Byrne, H Tilg - Gut, 2020 - gut.bmj.com
Non-alcoholic fatty liver disease (NAFLD) is a public health problem, affecting up to a third of
the world's adult population. Several cohort studies have consistently documented that …

The relationship between type 2 diabetes, NAFLD, and cardiovascular risk

C Caussy, A Aubin, R Loomba - Current diabetes reports, 2021 - Springer
Abstract Purpose of Review Nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes
mellitus (T2DM) are strongly associated. Both also associate with an increased risk of …

The Asian Pacific Association for the Study of the Liver clinical practice guidelines for the diagnosis and management of metabolic associated fatty liver disease

M Eslam, SK Sarin, VWS Wong, JG Fan… - Hepatology …, 2020 - Springer
Metabolic associated fatty liver disease (MAFLD) is the principal worldwide cause of liver
disease and affects nearly a quarter of the global population. The objective of this work was …

An international multidisciplinary consensus statement on MAFLD and the risk of CVD

XD Zhou, G Targher, CD Byrne, V Somers… - Hepatology …, 2023 - Springer
Background Fatty liver disease in the absence of excessive alcohol consumption is an
increasingly common condition with a global prevalence of~ 25–30% and is also associated …

Nonalcoholic Fatty Liver Disease and the Heart: JACC State-of-the-Art Review

EP Stahl, DS Dhindsa, SK Lee, PB Sandesara… - Journal of the American …, 2019 - jacc.org
Nonalcoholic fatty liver disease (NAFLD) and cardiovascular disease (CVD) are both
manifestations of end-organ damage of the metabolic syndrome. Through multiple …

Nonalcoholic fatty liver disease and cardiovascular disease: a review of shared cardiometabolic risk factors

E Muzurović, CCH Peng, MJ Belanger, D Sanoudou… - …, 2022 - Am Heart Assoc
The prevalence of nonalcoholic fatty liver disease (NAFLD) is rising. NAFLD/nonalcoholic
steatohepatitis (NASH) is associated not only with hepatic morbidity and mortality but also …

A meta-analysis on the global prevalence, risk factors and screening of coronary heart disease in nonalcoholic fatty liver disease

JZK Toh, XH Pan, PWL Tay, CH Ng, JN Yong… - Clinical …, 2022 - Elsevier
Background & Aims Cardiovascular disease remains the leading cause of death in patients
with nonalcoholic fatty liver disease (NAFLD). Studies examining the association of coronary …

NAFLD, and cardiovascular and cardiac diseases: Factors influencing risk, prediction and treatment

G Targher, KE Corey, CD Byrne - Diabetes & metabolism, 2021 - Elsevier
Background and aim Non-alcoholic fatty liver disease (NAFLD), affecting up to around 30%
of the world's adult population, causes considerable liver-related and extrahepatic morbidity …

Risk factors for cardiovascular disease in patients with metabolic-associated fatty liver disease: a machine learning approach

K Drożdż, K Nabrdalik, H Kwiendacz, M Hendel… - Cardiovascular …, 2022 - Springer
Background Nonalcoholic fatty liver disease is associated with an increased cardiovascular
disease (CVD) risk, although the exact mechanism (s) are less clear. Moreover, the …

Metabolic-associated fatty liver disease (MAFLD), diabetes, and cardiovascular disease: Associations with fructose metabolism and gut microbiota

K Drożdż, K Nabrdalik, W Hajzler, H Kwiendacz… - Nutrients, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is an increasingly common condition associated
with type 2 diabetes (T2DM) and cardiovascular disease (CVD). Since systemic metabolic …