Cardiovascular disease is the primary cause of morbidity and mortality among the diabetic
population. Both experimental and clinical evidence suggest that diabetic subjects are …

The term uraemic cardiomyopathy refers to the cardiac abnormalities that are seen in
patients with chronic kidney disease (CKD). Historically, this term was used to describe a …

Reactive oxygen species (ROS) are subcellular messengers in gene regulatory and signal
transduction pathways. In pathological situations, ROS accumulate due to excessive …

Insulin resistance (IR), a key component of the metabolic syndrome, precedes the
development of diabetes, cardiovascular disease, and Alzheimer's disease. Its etiological …

Lipid droplets (LDs) are ubiquitous organelles storing neutral lipids, including triacylglycerol
(TAG) and cholesterol ester. The properties of LDs vary greatly among tissues, and LD …

Cardiac oxidative stress is an early event associated with diabetic cardiomyopathy, triggered
by hyperglycemia. We tested the hypothesis that targeting left-ventricular (LV) reactive …

Background Myocardial infarction (MI) is a lethal manifestation of cardiovascular diseases.
Oxidative stress, inflammation, and subsequent cell death are known to play crucial roles in …

Evidence suggests that psychological and physical stress are relevant triggering factors for
the onset of type 1 diabetes (T1D) and type 2 diabetes (T2D). The underlying mechanisms …

Background Selenium and coenzyme Q10 are important antioxidants in the body. As the
intake of selenium is low in Europe, and the endogenous production of coenzyme Q10 …

Background: Recently, the European Food Safety Authority approved a claim concerning the
benefits of olive oil polyphenols for the protection of LDL from oxidation. Polyphenols could …