Dietary isothiocyanates inhibit cancer progression by modulation of epigenome

MK Sundaram, R Preetha, S Haque, N Akhter… - Seminars in Cancer …, 2022 - Elsevier
Cell cycle, growth, survival and metabolism are tightly regulated together and failure in
cellular regulation leads to carcinogenesis. Several signaling pathways like the PI3K, WNT …

Molecular mechanisms of the anti-cancer effects of isothiocyanates from cruciferous vegetables in bladder cancer

T Mastuo, Y Miyata, T Yuno, Y Mukae, A Otsubo… - Molecules, 2020 - mdpi.com
Bladder cancer (BC) is a representative of urological cancer with a high recurrence and
metastasis potential. Currently, cisplatin-based chemotherapy and immune checkpoint …

Anticancer activity, mechanism, and delivery of allyl isothiocyanate

A Tarar, S Peng, S Cheema, CA Peng - Bioengineering, 2022 - mdpi.com
Allyl isothiocyanate (AITC) is a phytochemical that is abundantly present in cruciferous
vegetables of the Brassicaceae family, such as cabbage, broccoli, mustard, wasabi, and …

Disabling the protease DDI2 attenuates the transcriptional activity of NRF1 and potentiates proteasome inhibitor cytotoxicity

A Northrop, JR Vangala, A Feygin… - International journal of …, 2020 - mdpi.com
Proteasome inhibition is used therapeutically to induce proteotoxic stress and trigger
apoptosis in cancer cells that are highly dependent on the proteasome. As a mechanism of …

[PDF][PDF] Cold plasma treatment on mustard green seeds and its effect on growth, isothiocyanates, antioxidant activity and anticancer activity of microgreens.

W Saengha, T Karirat, B Buranrat, K Matra… - 2021 - vivantechnologies.com
The aims of this work were to study growth, isothiocyanate (ITC), bioactive content,
antioxidant activity and anticancer activity of mustard green (MG) microgreens grown from …

Allyl isothiocyanate induces DNA damage and impairs DNA repair in human breast cancer MCF-7 cells

CL Liao, SF Peng, JC Chen, PY Chen… - Anticancer …, 2021 - ar.iiarjournals.org
Background/Aim: Ally lisothiocyanate (AITC), a constituent of naturally occurring
isothiocyanates (ITCs) found in some Brassica vegetables, has been previously …

The anti-tumoral potential of phosphonate analog of sulforaphane in Zebrafish xenograft model

M Rudzinska-Radecka, Ł Janczewski, A Gajda… - Cells, 2021 - mdpi.com
Isothiocyanates (ITCs) show strong activity against numerous human tumors. Five
structurally diverse ITCs were tested in vivo using the zebrafish embryos 6 and 48 h post …

Assessment of biological activities of chitosan Schiff base tagged with medicinal plants

AM Khan, OUR Abid, S Mir - Biopolymers, 2020 - Wiley Online Library
A chitosan Schiff base with an aromatic aldehyde was synthesized and characterized by
FTIR and NMR spectroscopies. Furthermore, the degree of substitution was calculated …

Influence of isolation techniques on the composition of glucosinolate breakdown products, their antiproliferative activity and gastrointestinal stability of allyl …

I Vrca, J Šćurla, N Kević, F Burčul, VČ Čulić… - European food research …, 2022 - Springer
Mustard seeds are used as a food, and spice due to their nutritive value, the presence of
biologically active compounds, and specific taste. Its morphology was investigated by optical …

[HTML][HTML] α-Mangostin and apigenin induced the necrotic death of BT474 breast cancer cells with autophagy and inflammation

T Ittiudomrak, S Puthong, T Palaga… - Asian Pacific Journal …, 2018 - journals.lww.com
Objective: To find new compounds in order to overcome the mainstay of metastatic breast
cancer due to the adverse side effects from, and increasing resistance to, current …