[HTML][HTML] Biofabrication methods for reconstructing extracellular matrix mimetics
A Aazmi, D Zhang, C Mazzaglia, M Yu, Z Wang… - Bioactive Materials, 2024 - Elsevier
In the human body, almost all cells interact with extracellular matrices (ECMs), which have
tissue and organ-specific compositions and architectures. These ECMs not only function as …
tissue and organ-specific compositions and architectures. These ECMs not only function as …
Advancing tissue decellularized hydrogels for engineering human organoids
The extracellular matrix plays a critical role in bioinstructing cellular self‐assembly and
spatial (re) configuration processes that culminate in human organoids in vitro generation …
spatial (re) configuration processes that culminate in human organoids in vitro generation …
Volumetric bioprinting of organoids and optically tuned hydrogels to build liver‐like metabolic biofactories
PN Bernal, M Bouwmeester, J Madrid‐Wolff… - Advanced …, 2022 - Wiley Online Library
Organ‐and tissue‐level biological functions are intimately linked to microscale cell–cell
interactions and to the overarching tissue architecture. Together, biofabrication and …
interactions and to the overarching tissue architecture. Together, biofabrication and …
Bioprinting microporous functional living materials from protein-based core-shell microgels
Living materials bring together material science and biology to allow the engineering and
augmenting of living systems with novel functionalities. Bioprinting promises accurate …
augmenting of living systems with novel functionalities. Bioprinting promises accurate …
Mammary tumor organoid culture in non‐adhesive alginate for luminal mechanics and high‐throughput drug screening
Mammary tumor organoids have become a promising in vitro model for drug screening and
personalized medicine. However, the dependency on the basement membrane extract …
personalized medicine. However, the dependency on the basement membrane extract …
Apical-out airway organoids as a platform for studying viral infections and screening for antiviral drugs
G Stroulios, T Brown, G Moreni, D Kondro, A Dei… - Scientific reports, 2022 - nature.com
Airway organoids are polarized 3D epithelial structures that recapitulate the organization
and many of the key functions of the in vivo tissue. They present an attractive model that can …
and many of the key functions of the in vivo tissue. They present an attractive model that can …
Engineering highly vascularized bone tissues by 3D bioprinting of granular prevascularized spheroids
Y Fang, M Ji, B Wu, X Xu, G Wang… - … Applied Materials & …, 2023 - ACS Publications
The convergence of 3D bioprinting with powerful manufacturing capability and cellular self-
organization that can reproduce intricate tissue microarchitecture and function is a promising …
organization that can reproduce intricate tissue microarchitecture and function is a promising …
Ethical challenges in organoid use
V Mollaki - BioTech, 2021 - mdpi.com
Organoids hold great promises for numerous applications in biomedicine and
biotechnology. Despite its potential in science, organoid technology poses complex ethical …
biotechnology. Despite its potential in science, organoid technology poses complex ethical …
Advancing organoid design through co-emergence, assembly, and bioengineering
Human adult stem cells and patient-derived induced pluripotent stem cells represent
promising tools to understand human biology, development, and disease. Under a …
promising tools to understand human biology, development, and disease. Under a …
Acoustic droplet printing tumor organoids for modeling bladder tumor immune microenvironment within a week
Z Gong, L Huang, X Tang, K Chen, Z Wu… - Advanced …, 2021 - Wiley Online Library
Current organoid models are limited by the incapability of rapidly fabricating organoids that
can mimic the immune microenvironment for a short term. Here, an acoustic droplet‐based …
can mimic the immune microenvironment for a short term. Here, an acoustic droplet‐based …